Chapter 15
Mass Spectrometry Fragmentation Methods
ספקטרומטריית מסות: פיצול אלקני ארוך שרשרת
The molecular ions of linear alkanes prefer to fragment at the carbon-carbon bond away from the end of the chain since the cleavage of an inner bond ...
ספקטרומטריית מסות: פרגמנטציה אלקנית מסועפת
This lesson delves into the mass spectrometry of branched alkane fragmentation. Branched alkanes possess secondary or tertiary carbon atoms, which ...
ספקטרומטריית מסות: פיצול ציקלואלקן
In mass spectrometry, cycloalkanes exhibit distinct fragmentation patterns due to the inherent stability of their molecular ions compared to linear or ...
ספקטרומטריית מסות: פיצול אלקני
Alkenes lose one electron from the unsaturated π bond upon ionization and form stable molecular ions. Further fragmentation of alkenes occurs through ...
ספקטרומטריית מסות: פיצול ציקלואלקן
The molecular ions of cycloalkenes undergo fragmentation via a retro-Diels–Alder reaction.
The reaction proceeds via the cleavage of two ...
ספקטרומטריית מסות: פיצול אלקין
The fragmentation of alkynes preferentially occurs at the carbon–carbon bond between the α and β carbon of the alkyne bond to generate a ...
ספקטרומטריית מסות: פיצול אלכוהול
Alcohols (R-OH) ionize to lose one non-bonded electron from the oxygen atom, forming molecular ions. Due to their tendency to fragment rapidly, the ...
ספקטרומטריית מסות: פיצול תרכובת ארומטית
Upon ionization, aromatic compounds generate a molecular ion that is observed as a prominent peak in their mass spectra. For example, the molecular ion ...
ספקטרומטריית מסות: פיצול אמין
Amines can be identified using mass spectroscopy based on their characteristic fragmentation patterns. The molecular ions of amines undergo fragmentation ...
Mass Spectrometry: Alkyl Halide Fragmentation
Chlorine isotopes exist as 35Cl and 37Cl in a 3:1 ratio, while bromine isotopes exist as 79Br and 81Br in a 1:1 ratio. The mass spectrum of alkyl halides ...
Mass Spectrometry: Alkyl Halide Fragmentation
Chlorine isotopes exist as 35Cl and 37Cl in a 3:1 ratio, while bromine isotopes exist as 79Br and 81Br in a 1:1 ratio. The mass spectrum of alkyl halides ...
ספקטרומטריית מסות: אלדהיד ופרגמנטציה של קטון
In mass spectrometry, the fragmentation of aliphatic aldehydes and ketones generally occurs through three key mechanisms: α-cleavage, inductive ...
ספקטרומטריית מסות: חומצה קרבוקסילית, אסטר ופיצול אמיד
The fragmentation patterns observed for compounds such as carboxylic acids, esters, and amides in the mass spectra include ⍺-cleavage and McLafferty ...
ספקטרומטריית מסות של יינון כימי (CI)
The molecular ion peak of a molecule in the mass spectrum provides vital information for molecular identification. However, conventional electron impact ...
ספקטרומטריית מסות ליינון אלקטרוספריי (ESI)
Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional ...
יינון ספיחה בלייזר בסיוע מטריצה (MALDI)
Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and ...
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