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Chapter 1

Princípios Farmacológicos Gerais

Descoberta de Medicamentos: Visão Geral
Descoberta de Medicamentos: Visão Geral
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for ...
Desenvolvimento Pré-clínico: Visão Geral
Desenvolvimento Pré-clínico: Visão Geral
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. ...
Ensaios Clínicos: Visão Geral
Ensaios Clínicos: Visão Geral
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific ...
Nomenclatura de Medicamentos
Nomenclatura de Medicamentos
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United ...
Regulação de Medicamentos
Regulação de Medicamentos
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. ...
Classes e Categorias de Medicamentos
Classes e Categorias de Medicamentos
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that ...
Ligações Fármaco-Receptor
Ligações Fármaco-Receptor
Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are ...
Interações Fármaco-Receptor
Interações Fármaco-Receptor
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. ...
Rotas de Administração de Medicamentos: Visão Geral
Rotas de Administração de Medicamentos: Visão Geral
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers ...
Rotas de Administração de Medicamentos: Entérica
Rotas de Administração de Medicamentos: Entérica
Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the ...
Rotas de Administração de Medicamentos: Parenteral
Rotas de Administração de Medicamentos: Parenteral
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability ...
Rotas Adicionais de Administração de Medicamentos
Rotas Adicionais de Administração de Medicamentos
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent ...
Medicamentos com e sem Prescrição e Medicamentos Órfãos
Medicamentos com e sem Prescrição e Medicamentos Órfãos
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including ...
Fatores que Afetam a Resposta aos Medicamentos: Visão Geral
Fatores que Afetam a Resposta aos Medicamentos: Visão Geral
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily ...
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