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Chapter 1

General Pharmacological Principles

Descubrimiento de fármacos: Visión general
Descubrimiento de fármacos: Visión general
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for ...
Desarrollo preclínico: descripción general
Desarrollo preclínico: descripción general
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. ...
Ensayos clínicos: descripción general
Ensayos clínicos: descripción general
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific ...
Nomenclatura de medicamentos
Nomenclatura de medicamentos
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United ...
Regulación de medicamentos
Regulación de medicamentos
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. ...
Clases y categorías de medicamentos
Clases y categorías de medicamentos
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that ...
Enlaces fármaco-receptor
Enlaces fármaco-receptor
Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are ...
Interacciones fármaco-receptor
Interacciones fármaco-receptor
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. ...
Vías de administración de medicamentos: descripción general
Vías de administración de medicamentos: descripción general
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers ...
Vías de administración de medicamentos: Enteral
Vías de administración de medicamentos: Enteral
Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the ...
Vías de administración de medicamentos: Parenteral
Vías de administración de medicamentos: Parenteral
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability ...
Vías adicionales de administración de medicamentos
Vías adicionales de administración de medicamentos
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent ...
Medicamentos con receta, de venta libre y huérfanos
Medicamentos con receta, de venta libre y huérfanos
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including ...
Factores que afectan a la respuesta a los fármacos: información general
Factores que afectan a la respuesta a los fármacos: información general
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily ...
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