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Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells

1.2K Views

10:19 min

May 12th, 2023

DOI :

10.3791/64390-v

May 12th, 2023


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Bispecific Antibody

Rozdziały w tym wideo

0:04

Introduction

0:39

Transfection of 293T Cells with Luciferase and Harvest of Viral Supernatant

3:22

Expansion and Transduction of Activated Human T Cells with Luciferase

6:20

Engraftment of Luciferase‐Transduced T cells in Immunocompromised Mice and In Vivo Imaging

7:41

Results: Evaluating the Anti‐Tumor Efficacy and Mechanism of T Cell‐Engaging Bispecific Antibodies

9:51

Conclusion

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