Chapter 17
Pharmacotherapy of the Epilepsies
Aperçu sur l’épilepsie et les crises d'épilepsie
Epilepsy is a chronic neurological disorder characterized by recurrent, unpredictable seizures.
Seizures result from abnormal electrical discharges in the ...
Classification des crises d’épilepsie :
Epilepsy is a chronic neurological disorder characterized by unpredictable seizures.
Seizures can be provoked by identifiable factors or occur ...
Les médicaments anti-épileptiques : les inhibiteurs des canaux sodiques
Antiepileptic drugs, essential in managing epilepsy, effectively prevent seizures by blocking the movement of sodium ions through channels in the ...
Les médicaments antiépileptiques : Le potentialisateur de la voie GABAergique
γ-aminobutyric acid or GABA pathway potentiators are drugs used to manage epilepsy by enhancing GABA neurotransmission, a critical inhibitory pathway ...
Les médicaments anti-épileptiques : les inhibiteurs calciques
Calcium channel blockers, primarily known for cardiovascular use, have also shown potential as antiepileptic drugs. They exert their effects by modulating ...
Les médicaments antiépileptiques : les antagonistes du glutamate
Glutamate is the primary excitatory neurotransmitter in the brain, essential for neuronal communication.
It plays a crucial role in synaptic transmission, ...
Les médicaments antiépileptiques : les modulateurs de la libération de neurotransmetteurs médiée par la protéine SV2A
Antiepileptic drugs, like levetiracetam and brivaracetam, leverage the synaptic vesicle protein SV2A to mitigate seizures.
SV2A is a transmembrane ...
Médicaments antiépileptiques : activateurs des canaux potassiques
The Antiepileptic drug ezogabine functions as a potassium channel activator by enhancing transmembrane potassium currents mediated by the KCNQ subtype of ...
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