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Chapter 17

Pharmacotherapy of the Epilepsies

간질 및 발작: 개요
간질 및 발작: 개요
Epilepsy is a chronic neurological disorder characterized by recurrent, unpredictable seizures. Seizures result from abnormal electrical discharges in the ...
발작: 분류
발작: 분류
Epilepsy is a chronic neurological disorder characterized by unpredictable seizures. Seizures can be provoked by identifiable factors or occur ...
항간질제: 나트륨 통로 차단제
항간질제: 나트륨 통로 차단제
Antiepileptic drugs, essential in managing epilepsy, effectively prevent seizures by blocking the movement of sodium ions through channels in the ...
항간질제: GABAergic 경로 증강제
항간질제: GABAergic 경로 증강제
γ-aminobutyric acid or GABA pathway potentiators are drugs used to manage epilepsy by enhancing GABA neurotransmission, a critical inhibitory pathway ...
항간질제: 칼슘 채널 차단제
항간질제: 칼슘 채널 차단제
Calcium channel blockers, primarily known for cardiovascular use, have also shown potential as antiepileptic drugs. They exert their effects by modulating ...
항간질제: 글루타메이트 길항제
항간질제: 글루타메이트 길항제
Glutamate is the primary excitatory neurotransmitter in the brain, essential for neuronal communication. It plays a crucial role in synaptic transmission, ...
항간질제: SV2A 단백질을 매개로 한 신경전달물질 방출 조절제
항간질제: SV2A 단백질을 매개로 한 신경전달물질 방출 조절제
Antiepileptic drugs, like levetiracetam and brivaracetam, leverage the synaptic vesicle protein SV2A to mitigate seizures. SV2A is a transmembrane ...
항간질제: 칼륨 채널 활성제
항간질제: 칼륨 채널 활성제
The Antiepileptic drug ezogabine functions as a potassium channel activator by enhancing transmembrane potassium currents mediated by the KCNQ subtype of ...
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