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Construction of a Human Aorta Smooth Muscle Cell Organ-On-A-Chip Model for Recapitulating Biomechanical Strain in the Aortic Wall

3.0K Views

11:47 min

July 6th, 2022

DOI :

10.3791/64122-v

July 6th, 2022


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Human Aorta

Chapters in this video

0:04

Introduction

1:03

Primary Human Aortic Smooth Muscle Cell Isolation

2:53

Preparation of PDMS Chip

5:29

PDMS Chip Surface Treatment and Sterilization

6:12

Cell Seeding on the PDMS Chip and Cell Stretching Process

8:23

Preparation of the Mechanical Control System

9:30

Results: An HASMC‐Organ‐On‐A‐Chip Model to Precisely Control the Parameters of the Biomechanical Strain on the Aortic Wall

11:03

Conclusion

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