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Core - Pharmacology

    Chapter 10

    Cardiovascular Drugs: Antiarrhythmic and Heart Failure Drugs

    10.1 : Electrophysiology of Normal Cardiac Rhythm01:19

    10.1 : Electrophysiology of Normal Cardiac Rhythm

    The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process ...

    2.1K views
    10.2 : Mechanism of Cardiac Arrhythmias01:28

    10.2 : Mechanism of Cardiac Arrhythmias

    Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various ...

    886 views
    10.3 : Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers01:22

    10.3 : Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers

    Class I antiarrhythmic drugs are used to treat various types of arrhythmias or irregular heart rhythms. These drugs block the sodium (Na+) channels in the ...

    1.2K views
    10.4 : Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers01:24

    10.4 : Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers

    Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in ...

    707 views
    10.5 : Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers01:12

    10.5 : Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers

    Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium ...

    902 views
    10.6 : Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers01:20

    10.6 : Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers

    Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in ...

    775 views
    10.7 : Pathophysiology of Cardiac Performance01:29

    10.7 : Pathophysiology of Cardiac Performance

    Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct ...

    542 views
    10.8 : Pathophysiology of Heart Failure01:17

    10.8 : Pathophysiology of Heart Failure

    Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and ...

    1.5K views
    10.9 : Heart Failure Drugs: Inotropic Agents01:26

    10.9 : Heart Failure Drugs: Inotropic Agents

    Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, ...

    516 views
    10.10 : Heart Failure Drugs: Diuretics01:22

    10.10 : Heart Failure Drugs: Diuretics

    Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that ...

    339 views
    10.11 : Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

    10.11 : Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

    The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the ...

    382 views
    10.12 : Heart Failure Drugs: β-Blockers01:22

    10.12 : Heart Failure Drugs: β-Blockers

    β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and ...

    315 views
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