JoVE Logo

Zaloguj się

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

9.7K Views

10:44 min

March 28th, 2017

DOI :

10.3791/55502-v

March 28th, 2017


Przeglądaj więcej filmów

Mass Spectrometry

Rozdziały w tym wideo

0:05

Title

0:48

Cell Culture

2:49

CYP Activity Quantification in Cell Cultures: Metabolic Probes, Inducers, and Inhibitors

4:30

CYP Activity Quantification in Cell Cultures: Medium Treatment

5:40

CYP Activity Quantification in Cell Cultures: Mass Spectrometry (MS)-based Quantification

6:49

CYP Activity Quantification in Cell Cultures: Probes Using Luminescence-based Methods

8:10

Results: Quantification of Metabolites Produced by tha Activity of CYP Enzymes Following Cell Incubation with CYP Inducers, Substrates, and Inhibitors

9:35

Conclusion

Powiązane Filmy

article

07:54

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy

13.1K Views

article

11:39

Extraction of Aqueous Metabolites from Cultured Adherent Cells for Metabolomic Analysis by Capillary Electrophoresis-Mass Spectrometry

8.3K Views

article

09:16

FIBS-enabled Noninvasive Metabolic Profiling

9.6K Views

article

08:06

Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass Spectrometry

9.1K Views

article

07:55

Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells

5.7K Views

article

05:59

Oxygen-Independent Assays to Measure Mitochondrial Function in Mammals

2.4K Views

article

14:42

Liquid Chromatography Coupled to Refractive Index or Mass Spectrometric Detection for Metabolite Profiling in Lysate-based Cell-free Systems

4.6K Views

article

07:06

Metabolic Analysis of Drosophila melanogaster Larval and Adult Brains

9.2K Views

article

04:07

Optical Photothermal Infrared-Fluorescence In Situ Hybridization (OPTIR-FISH)

1.1K Views

article

08:28

Targeted Metabolomics on Rare Primary Cells

1.8K Views

JoVE Logo

Prywatność

Warunki Korzystania

Zasady

Badania

Edukacja

O JoVE

Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone