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Core - Pharmacokinetics and Pharmacodynamics

    Chapter 1

    Pharmacokinetics and Pharmacodynamics: Introduction

    1.1 : Biopharmaceutics and Pharmacokinetics: Overview01:28

    1.1 : Biopharmaceutics and Pharmacokinetics: Overview

    Drugs come in various dosage forms, including solids, liquids, semisolids, or aerosols. These formulations deliver drugs at the site of action, triggering ...

    1.8K views
    1.2 : Pharmacokinetic Models: Overview01:20

    1.2 : Pharmacokinetic Models: Overview

    Pharmacokinetic models use mathematical analysis to express a drug's time course in the body. These models can simulate rates of a drug's ...

    578 views
    1.3 : Drug Concentration Versus Time Correlation01:15

    1.3 : Drug Concentration Versus Time Correlation

    Plasma drug levels, plotted at regular intervals, help track its time course in the body. For instance, consider a plot after a single oral dose. The drug ...

    610 views
    1.4 : Drug Concentrations: Measurements01:23

    1.4 : Drug Concentrations: Measurements

    Drug concentration represents the drug amount present in a biological sample. It helps assess the initial drug pharmacokinetics in the body. The samples ...

    324 views
    1.5 : Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs01:21

    1.5 : Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs

    Pharmacokinetic models view drugs within the body as dynamic entities and rely on calculus as a vital tool for quantitative drug movement analysis. ...

    1.0K views
    1.6 : Fundamental Mathematical Principles in Pharmacokinetics: Mathematical Expressions and Units01:19

    1.6 : Fundamental Mathematical Principles in Pharmacokinetics: Mathematical Expressions and Units

    Mathematical expressions help understand pharmacokinetic parameters by using equations to describe the relationships between different variables. For ...

    524 views
    1.7 : Fundamental Mathematical Principles in Pharmacokinetics: Rate and Order of Reaction01:15

    1.7 : Fundamental Mathematical Principles in Pharmacokinetics: Rate and Order of Reaction

    Pharmacokinetic models incorporate reaction order and rate to comprehend processes such as drug absorption and elimination. In pharmacokinetics, the rate ...

    274 views
    1.8 : Analysis of Population Pharmacokinetic Data01:12

    1.8 : Analysis of Population Pharmacokinetic Data

    Traditional pharmacokinetic methods involve taking multiple samples from a few individuals and estimating pharmacokinetic parameters. Despite their common ...

    224 views
    1.9 : Pharmacodynamics: Overview and Principles01:21

    1.9 : Pharmacodynamics: Overview and Principles

    Pharmacodynamics is the scientific study that explores the biochemical, cellular, and physiological effects of drugs on the body. Most drug effects result ...

    951 views
    1.10 : Structure-Activity Relationships and Drug Design01:28

    1.10 : Structure-Activity Relationships and Drug Design

    Drug design involves discovering new medications based on specific biological targets. It relies on structure-activity relationships, SAR, or quantitative ...

    510 views
    1.11 : Agonism and Antagonism: Quantification01:14

    1.11 : Agonism and Antagonism: Quantification

    Administration of drugs can lead to either agonist or antagonist effect. Agonism occurs when a drug activates a receptor, triggering a biological ...

    318 views
    1.12 : Drug Control Governance: Regulatory Bodies and Their Impact01:03

    1.12 : Drug Control Governance: Regulatory Bodies and Their Impact

    Drug control governance involves global regulatory bodies that standardize and control the safety and efficacy of pharmaceuticals, as well as prevent ...

    141 views
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