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Chapter 26

The Cytoskeleton II: Microtubules and Intermediate Filaments

미세소관
미세소관
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory ...
미세소관 불안정성
미세소관 불안정성
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound ...
미세소관 형성
미세소관 형성
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as ...
미세소관 관련 단백질(MAP)
미세소관 관련 단백질(MAP)
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are ...
미세소관의 불안정화
미세소관의 불안정화
The destabilization of microtubules can occur during different stages of the microtubule lifecycle, such as nucleation or elongation. It can take place at ...
미세소관 관련 운동 단백질
미세소관 관련 운동 단백질
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they ...
소기관(organelles)과 소포(vesicles)의 움직임
소기관(organelles)과 소포(vesicles)의 움직임
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These ...
복잡한 미세소관 구조의 조립
복잡한 미세소관 구조의 조립
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular ...
세포 운동성의 미세소관
세포 운동성의 미세소관
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form ...
섬모 운동의 메커니즘
섬모 운동의 메커니즘
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible ...
신호전달에서의 미세소관
신호전달에서의 미세소관
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like ...
미세소관을 안정화시키는 약물
미세소관을 안정화시키는 약물
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the ...
미세소관을 불안정하게 만드는 약물
미세소관을 불안정하게 만드는 약물
Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that ...
중간 필라멘트의 구조
중간 필라멘트의 구조
The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of ...
중간 필라멘트의 종류
중간 필라멘트의 종류
The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and ...
중간 필라멘트의 형성
중간 필라멘트의 형성
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two ...
중간 필라멘트의 분해
중간 필라멘트의 분해
Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to ...
셉틴스
셉틴스
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. ...
셉틴의 역할
셉틴의 역할
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate ...
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