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第9章

心血管薬: 降圧薬

心血管薬: 治療適応症に基づく分類
心血管薬: 治療適応症に基づく分類
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These ...
高血圧と血圧の調節
高血圧と血圧の調節
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage ...
降圧薬: 利尿薬の作用
降圧薬: 利尿薬の作用
Diuretics are antihypertensive drugs used to treat hypertension resulting from sodium and water retention. Sodium, vital for fluid balance and nerve or ...
降圧薬: サイアジド系利尿薬
降圧薬: サイアジド系利尿薬
Thiazide diuretics are sulfonamide derivatives featuring a benzothiadiazine ring system in their molecular structure. Based on this structure, thiazide ...
降圧薬: カリウム保持性利尿薬
降圧薬: カリウム保持性利尿薬
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the ...
降圧薬: ベータ 1 遮断薬の作用
降圧薬: ベータ 1 遮断薬の作用
β1-receptors are primarily located in the heart and kidneys. In cardiac myocytes, these receptors interact with neurotransmitters released by the ...
降圧薬: 非選択的ベータ遮断薬の作用
降圧薬: 非選択的ベータ遮断薬の作用
β receptors are classified into three subclasses: β1, β2, and β3. β1 receptors are primarily located in the heart and kidneys. ...
降圧薬: カルシウムチャネル遮断薬の作用
降圧薬: カルシウムチャネル遮断薬の作用
Calcium ions are essential to contract smooth muscle cells in blood vessels. They enter these cells through voltage-dependent calcium channels, ...
降圧薬: アンジオテンシン変換酵素阻害剤
降圧薬: アンジオテンシン変換酵素阻害剤
Angiotensin-converting enzyme (ACE), a vital component of the renin-angiotensin-aldosterone system, is abundant in lung endothelial cells. ACE converts ...
降圧薬: アンジオテンシン II 受容体拮抗薬
降圧薬: アンジオテンシン II 受容体拮抗薬
In the renin-angiotensin-aldosterone system, a hormone called angiotensin II plays a crucial role. It binds to the AT1 receptors in vascular smooth ...
降圧薬: 直接レニン阻害剤
降圧薬: 直接レニン阻害剤
The renin-angiotensin-aldosterone system (RAAS) is an intricate physiological pathway involving numerous enzymes and hormones, including renin, ...
降圧薬: 血管拡張薬
降圧薬: 血管拡張薬
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as ...
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