Laura Hulea

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.

mTOR as a central regulator of lifespan and aging.

PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.

Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin.

Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.

Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.

A hydride transfer complex reprograms NAD metabolism and bypasses senescence.

Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.

Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.

EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax.

CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.

ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.

PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity.

Protocol to perform polysome profiling in primary differentiating murine adipocytes.

Translational control of leukemic metabolism and disease progression.