CAS Key Laboratory of Nutrition and Metabolism,
Institute for Nutritional Sciences,
CAS Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences
Yuan-Na Lin is a Research Scholar in the Department of Oncology, Lombardi Cancer Center at Georgetown University School of Medicine, Washington DC. Dr. Lin is a board-certified visceral surgeon at University Hospital Hamburg-Eppendorf, Germany, where she has received her MD and Ph.D.
During her surgical residency, Dr. Lin has been working on the role of actin binding proteins in cancer cell development and metastasis in an interdisciplinary and translational approach. She has been focusing on the formins mDia1 and mDia3 in colon cancer metastasis and chromosomal instability by modulation of the cytoskeleton. She then moved to Georgetown University, Washington DC, USA, as a DFG (German Research Funding Organization) Research Scholar. Here, she set up an innovative 3D tumor spheroid co-culture platform to examine tumor cell – immune cell interactions, in order to reveal new resistance mechanisms towards T-cell mediated tumor cell killing.
As a clinician, Dr. Lin is particularly interested in bridging basic research with clinical application. Her ultimate goal is to improve immunotherapeutic treatment approaches in patients with pancreatic cancer.
Lugol chromoendoscopic screening for esophageal dysplasia/early squamous cell carcinoma in patients with esophageal symptoms in low-risk region in China.
Oncology letters Jul, 2015 | Pubmed ID: 26170975
Static compression regulates OPG expression in periodontal ligament cells via the CAMK II pathway.
Journal of applied oral science : revista FOB Nov-Dec, 2015 | Pubmed ID: 26814456
Study on the mitochondrial apoptosis pathways of small cell lung cancer H446 cells induced by Trichinella spiralis muscle larvae ESPs.
Parasitology Jan, 2017 | Pubmed ID: 28073393
Chinese oral herbal paste for the treatment of stable chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis.
Medicine Jul, 2019 | Pubmed ID: 31305473
Acupuncture treatment of lung-spleen Qi deficiency in stable chronic obstructive pulmonary disease: a randomized, open-label, controlled trial.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Dec, 2019 | Pubmed ID: 32186160
The Effects and Safety of Chinese Oral Herbal Paste on Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Evidence-based complementary and alternative medicine : eCAM , 2020 | Pubmed ID: 32308709
Mechanisms of immune regulation for acupuncture on chronic respiratory diseases.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Apr, 2022 | Pubmed ID: 35473354
Diagnostic performance of mycological tests for invasive pulmonary aspergillosis in non-haematological patients: protocol for a systematic review and meta-analysis.
BMJ open Aug, 2022 | Pubmed ID: 36038162
Prognostic Value of Late Gadolinium Enhancement in Left Ventricular Noncompaction: A Multicenter Study.
Diagnostics (Basel, Switzerland) Oct, 2022 | Pubmed ID: 36292149
[Progress of researches on anti-inflammatory mechanism of acupuncture underlying amelioration of chronic respiratory diseases].
Zhen ci yan jiu = Acupuncture research Feb, 2023 | Pubmed ID: 36858410
Acupuncture for dyspnea and breathing physiology in chronic respiratory diseases: A systematic review and meta-analysis of randomized controlled trials.
Heliyon May, 2024 | Pubmed ID: 38813170
Efficacy and cerebral mechanisms of acupuncture for chronic obstructive pulmonary disease: study protocol for a multicenter, randomized controlled neuroimaging trial.
Frontiers in neurology , 2024 | Pubmed ID: 38988597
Prenatal heavy metal exposure and pediatric asthma, allergic rhinitis, atopic dermatitis: a systematic review and meta-analysis.
Expert review of clinical immunology Nov, 2024 | Pubmed ID: 39109589
Human monkeypox infection: a family cluster in the midwestern United States.
The Journal of infectious diseases Nov, 2004 | Pubmed ID: 15499541
A tale of two clades: monkeypox viruses.
The Journal of general virology Oct, 2005 | Pubmed ID: 16186219
Detection of monkeypox virus with real-time PCR assays.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Jul, 2006 | Pubmed ID: 16731033
Genome sequence diversity and clues to the evolution of variola (smallpox) virus.
Science (New York, N.Y.) Aug, 2006 | Pubmed ID: 16873609
Orthopoxvirus pan-genomic DNA assay.
Journal of virological methods May, 2007 | Pubmed ID: 17254642
Monkeypox zoonotic associations: insights from laboratory evaluation of animals associated with the multi-state US outbreak.
The American journal of tropical medicine and hygiene Apr, 2007 | Pubmed ID: 17426184
Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimod.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Jun, 2007 | Pubmed ID: 17479930
ORF virus infection in children: clinical characteristics, transmission, diagnostic methods, and future therapeutics.
The Pediatric infectious disease journal Aug, 2007 | Pubmed ID: 17848888
On the origin of smallpox: correlating variola phylogenics with historical smallpox records.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17901212
Real-time PCR assay to identify variants of Vaccinia virus: implications for the diagnosis of bovine vaccinia in Brazil.
Journal of virological methods Sep, 2008 | Pubmed ID: 18602170
Transmission of atypical varicella-zoster virus infections involving palm and sole manifestations in an area with monkeypox endemicity.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Jan, 2009 | Pubmed ID: 19025497
The phylogenetics and ecology of the orthopoxviruses endemic to North America.
PloS one Oct, 2009 | Pubmed ID: 19865479
GC content-based pan-pox universal PCR assays for poxvirus detection.
Journal of clinical microbiology Jan, 2010 | Pubmed ID: 19906902
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA.
Journal of virological methods Oct, 2010 | Pubmed ID: 20643162
Novel deer-associated parapoxvirus infection in deer hunters.
The New England journal of medicine Dec, 2010 | Pubmed ID: 21190456
Vaccinia virus infections in martial arts gym, Maryland, USA, 2008.
Emerging infectious diseases Apr, 2011 | Pubmed ID: 21470473
Detection of North American orthopoxviruses by real time-PCR.
Virology journal Jun, 2011 | Pubmed ID: 21689420
Chasing Jenner's vaccine: revisiting cowpox virus classification.
PloS one , 2011 | Pubmed ID: 21858000
Investigation of the first laboratory-acquired human cowpox virus infection in the United States.
The Journal of infectious diseases Jul, 2012 | Pubmed ID: 22539811
Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001.
The Journal of infectious diseases Nov, 2012 | Pubmed ID: 22904336
Phylogenetic and ecologic perspectives of a monkeypox outbreak, southern Sudan, 2005.
Emerging infectious diseases Feb, 2013 | Pubmed ID: 23347770
Novel poxvirus in big brown bats, northwestern United States.
Emerging infectious diseases Jun, 2013 | Pubmed ID: 23735421
Orthopoxvirus variola infection of Cynomys ludovicianus (North American black tailed prairie dog).
Virology Sep, 2013 | Pubmed ID: 23809939
Specific qPCR assays for the detection of orf virus, pseudocowpox virus and bovine papular stomatitis virus.
Journal of virological methods Dec, 2013 | Pubmed ID: 24035807
Ocular molluscum contagiosum atypical clinical presentation.
The Pediatric infectious disease journal Jun, 2014 | Pubmed ID: 24830519
In vitro efficacy of brincidofovir against variola virus.
Antimicrobial agents and chemotherapy Sep, 2014 | Pubmed ID: 24957837
Novel poxvirus infection in 2 patients from the United States.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Jan, 2015 | Pubmed ID: 25301210
Zoonotic parapoxviruses detected in symptomatic cattle in Bangladesh.
BMC research notes Nov, 2014 | Pubmed ID: 25410770
Variola virus-specific diagnostic assays: characterization, sensitivity, and specificity.
Journal of clinical microbiology Apr, 2015 | Pubmed ID: 25673790
Human infection with a zoonotic orthopoxvirus in the country of Georgia.
The New England journal of medicine Mar, 2015 | Pubmed ID: 25806914
A phylogeographic investigation of African monkeypox.
Viruses Apr, 2015 | Pubmed ID: 25912718
Correction for Kondas et al., Variola Virus-Specific Diagnostic Assays: Characterization, Sensitivity, and Specificity.
Journal of clinical microbiology Aug, 2015 | Pubmed ID: 26195639
Novel Poxvirus Infection in an Immune Suppressed Patient.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Nov, 2015 | Pubmed ID: 26243783
Human Monkeypox in the Kivus, a Conflict Region of the Democratic Republic of the Congo.
The American journal of tropical medicine and hygiene Oct, 2015 | Pubmed ID: 26283752
Genomic Analysis, Phenotype, and Virulence of the Historical Brazilian Smallpox Vaccine Strain IOC: Implications for the Origins and Evolutionary Relationships of Vaccinia Virus.
Journal of virology Dec, 2015 | Pubmed ID: 26378174
An Investigation of a Cluster of Parapoxvirus Cases in Missouri, Feb-May 2006: Epidemiologic, Clinical and Molecular Aspects.
Animals : an open access journal from MDPI Feb, 2013 | Pubmed ID: 26487314
Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil.
Genome announcements Jun, 2016 | Pubmed ID: 27340056
Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft.
The Journal of infectious diseases Oct, 2016 | Pubmed ID: 27456708
Finishing monkeypox genomes from short reads: assembly analysis and a neural network method.
BMC genomics Aug, 2016 | Pubmed ID: 27585810
The genomes of three North American orthopoxviruses.
Virus genes Feb, 2017 | Pubmed ID: 27613417
Serro 2 Virus Highlights the Fundamental Genomic and Biological Features of a Natural Vaccinia Virus Infecting Humans.
Viruses Dec, 2016 | Pubmed ID: 27973399
Evaluation of the GeneXpert for Human Monkeypox Diagnosis.
The American journal of tropical medicine and hygiene Feb, 2017 | Pubmed ID: 27994107
A Pan-Lyssavirus Taqman Real-Time RT-PCR Assay for the Detection of Highly Variable Rabies virus and Other Lyssaviruses.
PLoS neglected tropical diseases Jan, 2017 | Pubmed ID: 28081126
A rapid Orthopoxvirus purification protocol suitable for high-containment laboratories.
Journal of virological methods May, 2017 | Pubmed ID: 28131867
Novel Orthopoxvirus Infection in an Alaska Resident.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Jun, 2017 | Pubmed ID: 28329402
Cowpox virus: What's in a Name?
Viruses May, 2017 | Pubmed ID: 28486428
Characterization of Eptesipoxvirus, a novel poxvirus from a microchiropteran bat.
Virus genes Dec, 2017 | Pubmed ID: 28685222
Two novel poxviruses with unusual genome rearrangements: NY_014 and Murmansk.
Virus genes Dec, 2017 | Pubmed ID: 28762208
Genome Sequences of Akhmeta Virus, an Early Divergent Old World Orthopoxvirus.
Viruses May, 2018 | Pubmed ID: 29757202
Multi-site evaluation of the LN34 pan-lyssavirus real-time RT-PCR assay for post-mortem rabies diagnostics.
PloS one , 2018 | Pubmed ID: 29768505
New Insights into the Evolutionary and Genomic Landscape of Molluscum Contagiosum Virus (MCV) based on Nine MCV1 and Six MCV2 Complete Genome Sequences.
Viruses Oct, 2018 | Pubmed ID: 30373153
Seasonal and interannual risks of dengue introduction from South-East Asia into China, 2005-2015.
PLoS neglected tropical diseases Nov, 2018 | Pubmed ID: 30412575
Exposure history, post-exposure prophylaxis use, and clinical characteristics of human rabies cases in China, 2006-2012.
Scientific reports Nov, 2018 | Pubmed ID: 30464190
Novel mass spectrometry based detection and identification of variants of rabies virus nucleoprotein in infected brain tissues.
PLoS neglected tropical diseases 12, 2018 | Pubmed ID: 30550539
Genome of Alaskapox Virus, A Novel Orthopoxvirus Isolated from Alaska.
Viruses Aug, 2019 | Pubmed ID: 31375015
Isolation and Characterization of Akhmeta Virus from Wild-Caught Rodents ( spp.) in Georgia.
Journal of virology Dec, 2019 | Pubmed ID: 31554682
Using the LN34 Pan-Lyssavirus Real-Time RT-PCR Assay for Rabies Diagnosis and Rapid Genetic Typing from Formalin-Fixed Human Brain Tissue.
Viruses 01, 2020 | Pubmed ID: 31963651
The origins and genomic diversity of American Civil War Era smallpox vaccine strains.
Genome biology Jul, 2020 | Pubmed ID: 32684155
Exportation of Monkeypox Virus From the African Continent.
The Journal of infectious diseases Apr, 2022 | Pubmed ID: 32880628
Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION.
Viruses Nov, 2020 | Pubmed ID: 33158200
Evaluation of Two Real-Time, TaqMan Reverse Transcription-PCR Assays for Detection of Rabies Virus in Circulating Variants from Argentina: Influence of Sequence Variation.
Viruses Dec, 2020 | Pubmed ID: 33375530
Clinical and Epidemiological Findings from Enhanced Monkeypox Surveillance in Tshuapa Province, Democratic Republic of the Congo During 2011-2015.
The Journal of infectious diseases Jun, 2021 | Pubmed ID: 33728469
Geographic distribution and genetic characterization of poxviruses from human infections in Georgia, 2009-2014.
Archives of virology Jun, 2021 | Pubmed ID: 33745070
Findings from the initial Stepwise Approach to Rabies Elimination (SARE) Assessment in China, 2019.
PLoS neglected tropical diseases Mar, 2021 | Pubmed ID: 33780454
Assessing clinicians' Post-Exposure Prophylaxis recommendations for rabies virus exposures in Hunan Province, China.
PLoS neglected tropical diseases Jul, 2021 | Pubmed ID: 34228714
Detection of Apparent Early Rabies Infection by LN34 Pan-Lyssavirus Real-Time RT-PCR Assay in Pennsylvania.
Viruses Aug, 2022 | Pubmed ID: 36146650
Multiple lineages of monkeypox virus detected in the United States, 2021-2022.
Science (New York, N.Y.) Nov, 2022 | Pubmed ID: 36264825
Strategies to inTerrupt RAbies Transmission for the Elimination Goal by 2030 In China (STRATEGIC): a modelling study.
BMC medicine Mar, 2023 | Pubmed ID: 36927437
Fatal Human Rabies Infection With Suspected Host-Mediated Failure of Post-Exposure Prophylaxis Following a Recognized Zoonotic Exposure-Minnesota, 2021.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Oct, 2023 | Pubmed ID: 36988328
How the Orthodox Features of Orthopoxviruses Led to an Unorthodox Mpox Outbreak: What We've Learned, and What We Still Need to Understand.
The Journal of infectious diseases Mar, 2024 | Pubmed ID: 37861379
Comparing the genetic typing methods for effective surveillance and rabies control in Georgia.
Frontiers in microbiology , 2023 | Pubmed ID: 38107855
Genetic Tracking of a Rabid Coyote (Canis latrans) Detected beyond a Rabies Enzootic Area in West Virginia, USA.
Journal of wildlife diseases Jul, 2024 | Pubmed ID: 38685759
Reemergence of a Big Brown Bat Variant in Striped Skunks in Flagstaff, Arizona, USA, 2021-2023.
Vector borne and zoonotic diseases (Larchmont, N.Y.) Aug, 2024 | Pubmed ID: 38775097
Fatal borealpox in an immunosuppressed patient treated with antivirals and vaccinia immunoglobulin - Alaska, 2023.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Nov, 2024 | Pubmed ID: 39499668
Optimization of pan-lyssavirus LN34 assay for streamlined rabies diagnostics by real-time RT-PCR.
Journal of virological methods Apr, 2025 | Pubmed ID: 39580120
Orthopoxvirus Genome Sequencing, Assembly, and Analysis.
Methods in molecular biology (Clifton, N.J.) , 2025 | Pubmed ID: 39621260
Yaolei Mi1,2,
Zhihui Zhu3,
Guangtao Qian3,
Yu Li4,
Xiangxiao Meng1,
Jianping Xue3,
Qingfu Chen5,
Wei Sun1,
Yuhua Shi1,2
1Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences,
2Artemisinin Research Center, China Academy of Chinese Medical Sciences,
3College of Life Science, Huaibei Normal University,
4, Economic Crop Research Institute Sichuan Academy of Agriculture Sciences,
5Research Center of Buckwheat Industry Technology, Guizhou Normal University
Yu Li1,
Fengjiao Zhou2,
Hui Zhang1,
Xi Chen1,
Man Yin1,
Mi Tang1,
Jianfeng Zhang3,
Zeyi Lv1,
Hao Yang1,
Yue Huang1,
XinRong Li1
1Integrated Chinese and Western Medicine Ear, Nose, Throat, Head, and Neck Surgery, Hospital of Chengdu University of Traditional Chinese Medicine,
2Hospital of Chengdu University of Traditional Chinese Medicine, Hospital of Chengdu University of Traditional Chinese Medicine,
3, Chongqing Jiangjin District Hospital of Traditional Chinese Medicine
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