Questo lavoro è stato sostenuto in parte da KAKENHI (25708020, 15K13812, 15H00860, 15H00986, 16H02081) dal JSPS / MEXT Japan, dalla Fondazione Asahi Glass e dall&#39;iniziativa pre-strategica dell&#39;Università di Tsukuba, &quot;Ensemble della luce con le questioni e la vita&quot;.

1. Protocolli di fabbricazione di microsfere di polimeri <ol><li> Metodo di diffusione del vapore <ol><li> Sciogliere 2 mg di polimeri coniugati come P1 (poli [(9,9-dioctilfluorene-2,7-diil) - alt- (5-ottiltieno [3,4- c ] pirrolo-4,6-dione- 3-diil)) 28 e P2 (poli [(N- (2-eptilundecil) carbazolo-2,7-diil) - alt- (4,8-bis [(dodecil) carbonil] benzo [1,2- : 4,5- b &#39;] ditiofene-2,6-diil)] 28 , in 2 ml di cloroformio (un buon solvente) in una fiala da 5 ml. </li><li> Mettere 5 mL di metanolo (un povero solvente) in una fiala di 50 mL. </li><li> Inserire il flaconcino da 5 ml contenente la soluzione cloroformica del polimero nel flaconcino da 50 ml contenente metanolo. </li><li> Fissare il flaconcino da 50 ml e tenerlo per 3 giorni a 25 ° C per consentire la precipitazione delle microsfere del polimero. </li></ol></li><li> Metodo di mini-emulsione <ol><li> Sciogliere 5 mg di polimeri coniugati, come polY [9,9-di-n-ottilfluorenil-2,7-diil] (PFO) e poli [2-metossi-5- (3 &#39;, 7&#39;-dimetilattilossi) -1,4-fenilenvinilen] (MDMOPPV) In 1 mL di cloroformio. </li><li> Sciogliere 30 mg (~ 50 mM) di dodecil solfato di sodio (SDS) in 2 ml di acqua deionizzata. </li><li> Aggiungere 100 μL della soluzione cloroformica del polimero a 2 ml di acqua contenente SDS. </li><li> Mescolare vigorosamente la miscela di cloroformio / acqua usando un omogenizzatore ultra veloce a 30.000 giri / min per 2 minuti per emulsionare la soluzione. </li><li> Conservare per 1 giorno senza soffiare il flaconcino per evaporare il cloroformio. </li><li> Centrifugare la dispersione in un tubo di microcentrifuga da 1,5 ml per 5 min a 2.200 x g. Rimuovere la soluzione acquosa di supernatante contenente SDS. </li><li> Aggiungere 2 ml di acqua deionizzata e agitare energicamente. </li><li> Ripetere la fase 1.2.6 e 1.2.7 tre volte per lavare la SDS residua. </li></ol></li><li> Metodo di precipitazione dell&#39;interfaccia </li><li> Sciogliere 200 μg di polistirene (PS) e 10 μG di colorante fluorescente (dipirreno di boro, BODIPY) a 0,2 mL di tetraidrofurano (THF). </li><li> Versare delicatamente la soluzione di THF su 1 ml dello strato d&#39;acqua. </li><li> Conservare il THF / acqua separato a due strati per 6 ore senza coperchio della fiala per consentire la precipitazione delle microsfere del polimero. </li></ol> 2. Misurazione micro-fotoluminescenza (μ-PL) <ol><li> Preparazione del campione <ol><li> Diluire una sospensione delle microsfere preparate nella sezione 1 in una soluzione non solvente ( ossia metanolo o acqua deionizzata). </li><li> Spin-cast una goccia (20-30 μL) della sospensione diluita delle microsfere su un substrato di quarzo usando uno spin-coater (tipicamente 2.000 giri / min per 50 s). </li><li> Asciugare in aria la pellicola di colata risultante finché i solventi non sono completamente evaporati (~ 5 min). </li></ol></li><li> Setup sperimentale <ol><li> Mettere il substrato di quarzo (15 x 15 x 0,5 mm 3 ) sulla fase di campionamento di un micr. Otticooscope. </li><li> Trova microsfere ben definite che sono isolate da altre sfere e adatte alla misura μ-PL. </li><li> Selezionare un laser ( cioè lunghezza d&#39;onda, onda continua o impulso, tempo di irradiazione, integrazione, ecc. ). </li><li> Selezionare l&#39;ingrandimento dell&#39;obiettivo. </li></ol></li><li> misure <ol><li> Utilizzare un fascio laser concentrato per irradiare la microsfera. Utilizzare la seguente condizione laser: cw o laser pulsato con lunghezze d&#39;onda di eccitazione ( λ ex ) di 405 nm (cw), 450 nm (cw), 355 nm (laser a impulsi, frequenza 1 kHz, durata dell&#39;impulso, 7 ns) e 470 Nm (laser a impulsi, frequenza, 2,5 MHz, durata dell&#39;impulso, 70 ps). </li><li> Registrare lo spettro PL sul punto eccitato usando uno spettrometro con una griglia di 300 o 1.200 scanalature mm -1 . </li><li> Prendi un&#39;immagine fluorescente. </li><li> Cambiare il punto di eccitazione spostando lo stadio di campionamento. </li><li> Cambiare il punto di rilevamento inclinando il collimatore(se necessario). </li></ol></li></ol> 3. Tecnica di micromanipolazione <ol><li> Manipolazione di microsfere <ol><li> Impostare un substrato di quarzo su cui le microsfere sono immobilizzate sulla fase di campionamento di un microscopio ottico. </li><li> Trovare una microsfera ben definita appropriata per la misura μ-PL. </li><li> Impostare un micro-ago in plastica su un dispositivo di micro-manipolazione. </li><li> Spostare il microsago utilizzando un joystick controllato dal computer per raccogliere una microsfera. </li><li> Spostare la microsfera e collegarlo ad un&#39;altra microsfera. </li><li> Misurare μ-PL dalla microsfera collegata. </li></ol></li></ol>

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The selection of a good solvent and non-solvent is very important for the self-assembly of well-defined microspheres. If the solubility of a polymer is too high, precipitation will not occur. Also, in general, &#960;-conjugated polymers are hydrophobic, so polar non-solvents, such as MeOH, acetonitrile, and acetone, are often used in the vapor diffusion method to minimize the surface energy required to form a spherical shape. The interface precipitation method is often adopted for the preparation of dye-doped polymer mic...

Le particelle di nano polimero / micro-dimensioni sono ampiamente utilizzate per una varietà di applicazioni, tra cui supporto per catalizzatore, riempitivi di cromatografia a colonna, agenti di somministrazione di farmaci, sonde fluorescenti per il monitoraggio delle celle, supporti ottici e così via 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 . In particolare, i polimeri π-coniugati presentano proprietà intrinseche luminescenti e di carica che beneficiano di applicazioni ottiche, elettroniche e optoelettroniche usando sfere polimeriche 10 , 11 , 12 , 13 , 14 , in particolare applicazioni laser usando organi softMateriali anici 15 , 16 , 17 . Ad esempio, l&#39;integrazione tridimensionale di sfere con centinaia di diametri di nanometro forma cristalli colloidali, che mostrano lacune di banda fotonica ad una determinata lunghezza d&#39;onda 18 , 19 . Quando la luce è confinata nella struttura periodica dell&#39;interscono, l&#39;azione di lucentezza appare al centro della fascia di arresto. D&#39;altra parte, quando le dimensioni delle sfere aumentano alla scala multi-micrometrica, la luce è confinata all&#39;interno di un&#39;unica microsfera attraverso la riflessione interna totale all&#39;interfaccia polimero / aria 20 . La propagazione dell&#39;onda di luce alla circonferenza massima provoca interferenze, portando alla comparsa di una modalità risonante con linee di emissione nitide e periodiche. Queste modalità ottiche sono le cosiddette &quot;modalità gallerie sussurrate&quot; (WGMs). Il termine &quot;sussurra la galleria&quot; ha origine daCattedrale di St. Paul a Londra, dove le onde sonore si propagano lungo la circonferenza del muro, permettendo di sentire gli sussurri da una persona dall&#39;altra parte della galleria. Poiché la lunghezza d&#39;onda della luce è sulla scala sub-micrometra, che è molto più piccola delle onde sonore, una grande cupola non è necessaria per il WGM della luce: piccole navi micrometriche e ben definite, come microsfere, microdisc , E microcristalli, soddisfano le condizioni WGM. L&#39;equazione 1 è una forma semplice della condizione risonante WGM 21 : Nπd = lλ (1) Dove n è l&#39;indice di rifrazione del risonatore, d è il diametro, l è il numero intero e λ è la lunghezza d&#39;onda della luce. La parte sinistra di (1) è la lunghezza del percorso ottico attraverso una propagazione di cerchio. Quando il percorso ottico coincide con ilIntero multiplo della lunghezza d&#39;onda, si verifica una risonanza, mentre all&#39;altra lunghezza d&#39;onda l&#39;onda di luce si riduce all&#39;arrotondamento. Questo documento introduce diversi metodi sperimentali per preparare microsfere per i risonatori WGM da polimeri coniugati in soluzione: diffusione del vapore 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , mini-emulsione 31 e precipitazione d&#39;interfaccia 32 . Ogni metodo ha caratteristiche uniche; Per esempio, il metodo di diffusione del vapore fornisce microsfere ben definite con sfericità molto elevata e superfici lisce, ma solo polimeri a bassa cristallinità possono formare queste microsfere. D&#39;altra parte, per la mini-emulsioneMetodo, diversi tipi di polimeri coniugati, compresi i polimeri ad alta cristallina, possono formare sfere, ma la morfologia superficiale è inferiore a quella ottenuta dal metodo di diffusione del vapore. Il metodo di precipitazione dell&#39;interfaccia è preferibile per la creazione di microsfere di polimeri non coniugati con coloranti. In tutti i casi, la selezione del solvente e del non solvente svolge un ruolo importante nella formazione della morfologia sferica. Nella seconda metà di questo documento sono state presentate tecniche μ-PL e micro-manipolazione. Per la tecnica μ-PL, le microsfere sono disperse su un substrato e un fascio laser concentrato, tramite un obiettivo microscopico, viene utilizzato per irradiare una singola microsfera isolata 24 . Il PL generato da una sfera viene rilevato da uno spettrometro attraverso l&#39;obiettivo del microscopio. Lo spostamento della fase di campionamento può variare la posizione del punto di eccitazione. Il punto di rilevamento è anche variabile inclinando l&#39;ottica del collimatore dell&#39;exciFascio laser rispetto all&#39;asse ottico del percorso di rilevazione 28 , 32 . Per studiare la propagazione della luce intersferale e la conversione della lunghezza d&#39;onda, è possibile utilizzare la tecnica di micro-manipolazione 32 . Per collegare diverse microsfere con differenti proprietà ottiche, è possibile prelevare una sfera usando un microsago e posizionandolo su un&#39;altra sfera. In combinazione con le tecniche di micromanipolazione e il metodo μ-PL, possono essere eseguite varie misurazioni ottiche usando sfere polimeriche coniugate, che vengono preparate con un semplice metodo di autoassemblaggio. Questa carta video sarà utile ai lettori che desiderano utilizzare materiali polimerici morbidi per applicazioni ottiche.

<table><tbody><tr><td>polystyrene</td><td>Aldrich</td><td>132427-25G</td><td></td></tr><tr><td>sodium dodecylsulfate</td><td>Kanto Kagaku</td><td>372035-31</td><td></td></tr><tr><td>tetrahydrofuran</td><td>Wako</td><td>206-08744</td><td></td></tr><tr><td>chloroform</td><td>Wako</td><td>038-18495</td><td></td></tr><tr><td>methanol</td><td>Wako</td><td>139-13995</td><td></td></tr><tr><td>Poly(9,9-di-n-octylfluorenyl-2,7-diyl)</td><td>Aldrich</td><td>571652-500MG</td><td></td></tr><tr><td>Poly[2-methoxy-5-(3&amp;prime;,7&amp;prime;-dimethyloctyloxy)-1,4-phenylenevinylene] (MDMOPPV)</td><td>Aldrich</td><td>546461-1G</td><td></td></tr><tr><td>poly[(9,9-dioctylfluorene-2,7-diyl)-alt-(5-octylthieno[3,4-c]pyrrole-4,6-dione-1,3-diyl)] (P1)</td><td>synthesized</td><td>-</td><td>reference 28</td></tr><tr><td>poly[(N-(2-heptylundecyl)carbazole-2,7-diyl)-alt-(4,8-bis[(dodecyl)carbonyl]benzo[1,2-b:4,5-b&amp;prime;]dithiophene-2,6-diyl)] (P2)</td><td>synthesized</td><td>-</td><td>reference 28</td></tr><tr><td>fluorescent dye (boron dipyrrin; BODIPY)</td><td>synthesized</td><td>-</td><td>reference 32</td></tr><tr><td>Optical Microscope</td><td>Nicon</td><td>Eclipse LV-N</td><td></td></tr><tr><td>laser_405 nm</td><td>Hutech</td><td>DH405-10-5</td><td></td></tr><tr><td>Spectrometer</td><td>Lambda Vision</td><td>LV-MC3/T</td><td></td></tr><tr><td>Homogenizer</td><td>Microtech Nichion</td><td>Physcotron NS-360D</td><td></td></tr><tr><td>micromanipulation</td><td>Microsupport</td><td>Quick Pro QP-3RH</td><td></td></tr></tbody></table>

fabrication of polymer microspheres for optical resonator and laser applications

Questo articolo descrive tre metodi per la preparazione di microsfere fluorescenti che comprendono polimeri π-coniugati o non coniugati: diffusione del vapore, precipitazione dell&#39;interfaccia e mini-emulsione. In tutti i metodi, le sfere di dimensioni micrometriche ben definite sono ottenute da un processo di auto-assemblaggio in soluzione. Il metodo di diffusione del vapore può provocare sfere con la più alta sfericità e superficie liscia, tuttavia i tipi di polimeri in grado di formare queste sfere sono limitate. D&#39;altra parte, nel metodo di mini-emulsione, le microsfere possono essere fatte da vari tipi di polimeri, anche da polimeri altamente cristallini con coplanari, π-coniugati spine. Le proprietà fotoluminescenti (PL) da singole microsfere isolate sono inusuali: il PL è confinato all&#39;interno delle sfere, si propaga alla circonferenza delle sfere attraverso la riflessione interna totale all&#39;interfaccia polimero / aria e si auto-interferisce per mostrare una resonante forte e periodica Linee PL. Questi resonatiLe modalità g sono le cosiddette &quot;modalità gallerie sussurrate&quot; (WGMs). Questo lavoro illustra come misurare WGM PL da singole sfere isolate utilizzando la tecnica della micro-fotoluminescenza (μ-PL). In questa tecnica, un raggio laser concentrato irradia un&#39;unica microsfera, e la luminescenza viene rilevata da uno spettrometro. Una tecnica di micromanipolazione viene quindi usata per collegare le microsfere una per una e per dimostrare la propagazione PL e la conversione del colore da microsfere accoppiate su eccitazione al perimetro di una sfera e rilevazione di PL dall&#39;altra microsfera. Queste tecniche, μ-PL e micromanipolazione, sono utili per gli esperimenti sull&#39;applicazione micro-ottica utilizzando materiali polimerici.

La figura 1 mostra le rappresentazioni schematiche del metodo di diffusione del vapore (a), del metodo di mini-emulsione (b) e del metodo di precipitazione dell&#39;interfaccia (c). Per il metodo di diffusione del vapore ( Figura 1a ), un flaconcino da 5 mL contenente una soluzione CHCl3 di polimeri (0,5 mg mL -1 , 2 mL) è stato posto in un flaconcino da 50 mL contenente 5 mL di un non solvente, come MeOH . Il flacon...

Watch this Scientific Journal Video about Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications at JoVE.com

Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Sono presentati i protocolli per la sintesi di microsfere da polimeri, la manipolazione delle microsfere e le misure di micro-fotoluminescenza.

Fabbricazione di microsfere di polimeri per risonatore ottico e applicazioni laser

This paper describes three methods of preparing fluorescent microspheres comprising &#960;-conjugated or non-conjugated polymers: vapor diffusion, ...

fabrication-polymer-microspheres-for-optical-resonator-laser

Universidad de Cartagena UDEC

Research

JoVE Journal

Engineering

14.0K Views.  University of Tsukuba.  Sono presentati i protocolli per la sintesi di microsfere da polimeri, la manipolazione delle microsfere e le misure di micro-fotoluminescenza. 

Video: Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Fabrication of Silica Ultra High Quality Factor Microresonators

Whispering gallery resonant cavities confine light in circular orbits at their periphery.1-2 The photon storage lifetime in the cavity, quantified by the quality factor (Q) of the cavity, can be in excess of 500ns for cavities with Q factors above 100 million. As a result of their low material losses, silica microcavities have demonstrated some of the longest photon lifetimes to date1-2. Since a portion of the circulating light extends outside the resonator, these devices can also be used to probe the surroundings. This interaction has enabled numerous experiments in biology, such as single molecule biodetection and antibody-antigen kinetics, as well as discoveries in other fields, such as development of ultra-low-threshold microlasers, characterization of thin films, and cavity quantum electrodynamics studies.3-7
The two primary silica resonant cavity geometries are the microsphere and the microtoroid. Both devices rely on a carbon dioxide laser reflow step to achieve their ultra-high-Q factors (Q&gt;100 million).1-2,8-9 However, there are several notable differences between the two structures. Silica microspheres are free-standing, supported by a single optical fiber, whereas silica microtoroids can be fabricated on a silicon wafer in large arrays using a combination of lithography and etching steps. These differences influence which device is optimal for a given experiment.
Here, we present detailed fabrication protocols for both types of resonant cavities. While the fabrication of microsphere resonant cavities is fairly straightforward, the fabrication of microtoroid resonant cavities requires additional specialized equipment and facilities (cleanroom). Therefore, this additional requirement may also influence which device is selected for a given experiment.
Introduction
An optical resonator efficiently confines light at specific wavelengths, known as the resonant wavelengths of the device. 1-2 The common figure of merit for these optical resonators is the quality factor or Q. This term describes the photon lifetime (&tau;o) within the resonator, which is directly related to the resonator's optical losses. Therefore, an optical resonator with a high Q factor has low optical losses, long photon lifetimes, and very low photon decay rates (1/&tau;o). As a result of the long photon lifetimes, it is possible to build-up extremely large circulating optical field intensities in these devices. This very unique property has allowed these devices to be used as laser sources and integrated biosensors.10
A unique sub-class of resonators is the whispering gallery mode optical microcavity. In these devices, the light is confined in circular orbits at the periphery. Therefore, the field is not completely confined within the device, but evanesces into the environment. Whispering gallery mode optical cavities have demonstrated some of the highest quality factors of any optical resonant cavity to date.9,11 Therefore, these devices are used throughout science and engineering, including in fundamental physics studies and in telecommunications as well as in biodetection experiments. 3-7,12
Optical microcavities can be fabricated from a wide range of materials and in a wide variety of geometries. A few examples include silica and silicon microtoroids, silicon, silicon nitride, and silica microdisks, micropillars, and silica and polymer microrings.13-17 The range in quality factor (Q) varies as dramatically as the geometry. Although both geometry and high Q are important considerations in any field, in many applications, there is far greater leverage in boosting device performance through Q enhancement. Among the numerous options detailed previously, the silica microsphere and the silica microtoroid resonator have achieved some of the highest Q factors to date.1,9 Additionally, as a result of the extremely low optical loss of silica from the visible through the near-IR, both microspheres and microtoroids are able to maintain their Q factors over a wide range of testing wavelengths.18 Finally, because silica is inherently biocompatible, it is routinely used in biodetection experiments.
In addition to high material absorption, there are several other potential loss mechanisms, including surface roughness, radiation loss, and contamination loss.2 Through an optimization of the device size, it is possible to eliminate radiation losses, which arise from poor optical field confinement within the device. Similarly, by storing a device in an appropriately clean environment, contamination of the surface can be minimized. Therefore, in addition to material loss, surface scattering is the primary loss mechanism of concern.2,8
In silica devices, surface scattering is minimized by using a laser reflow technique, which melts the silica through surface tension induced reflow. While spherical optical resonators have been studied for many years, it is only with recent advances in fabrication technologies that researchers been able to fabricate high quality silica optical toroidal microresonators (Q&gt;100 million) on a silicon substrate, thus paving the way for integration with microfluidics.1
The present series of protocols details how to fabricate both silica microsphere and microtoroid resonant cavities. While silica microsphere resonant cavities are well-established, microtoroid resonant cavities were only recently invented.1 As many of the fundamental methods used to fabricate the microsphere are also used in the more complex microtoroid fabrication procedure, by including both in a single protocol it will enable researchers to more easily trouble-shoot their experiments.

We describe the use of a carbon dioxide laser reflow technique to fabricate silica resonant cavities, including free-standing microspheres and on-chip microtoroids. The reflow method removes surface imperfections, allowing long photon lifetimes within both devices. The resulting devices have ultra high quality factors, enabling applications ranging from telecommunications to biodetection.

Fabbricazione di Microrisonatori silice Ultra High Quality Factor

Whispering gallery resonant cavities confine light in circular orbits at their periphery.1-2 The photon storage lifetime in the cavity, quantified by the ...

Ricerca

Ingegneria

Fabricating Metamaterials Using the Fiber Drawing Method

Metamaterials are man-made composite materials, fabricated by assembling components much smaller than the wavelength at which they operate 1. They owe their electromagnetic properties to the structure of their constituents, instead of the atoms that compose them. For example, sub-wavelength metal wires can be arranged to possess an effective electric permittivity that is either positive or negative at a given frequency, in contrast to the metals themselves 2. This unprecedented control over the behaviour of light can potentially lead to a number of novel devices, such as invisibility cloaks 3, negative refractive index materials 4, and lenses that resolve objects below the diffraction limit 5. However, metamaterials operating at optical, mid-infrared and terahertz frequencies are conventionally made using nano- and micro-fabrication techniques that are expensive and produce samples that are at most a few centimetres in size 6-7. Here we present a fabrication method to produce hundreds of meters of metal wire metamaterials in fiber form, which exhibit a terahertz plasmonic response 8. We combine the stack-and-draw technique used to produce microstructured polymer optical fiber 9 with the Taylor-wire process 10, using indium wires inside polymethylmethacrylate (PMMA) tubes. PMMA is chosen because it is an easy to handle, drawable dielectric with suitable optical properties in the terahertz region; indium because it has a melting temperature of 156.6 &deg;C which is appropriate for codrawing with PMMA. We include an indium wire of 1 mm diameter and 99.99% purity in a PMMA tube with 1 mm inner diameter (ID) and 12 mm outside diameter (OD) which is sealed at one end. The tube is evacuated and drawn down to an outer diameter of 1.2 mm. The resulting fiber is then cut into smaller pieces, and stacked into a larger PMMA tube. This stack is sealed at one end and fed into a furnace while being rapidly drawn, reducing the diameter of the structure by a factor of 10, and increasing the length by a factor of 100. Such fibers possess features on the micro- and nano- scale, are inherently flexible, mass-producible, and can be woven to exhibit electromagnetic properties that are not found in nature. They represent a promising platform for a number of novel devices from terahertz to optical frequencies, such as invisible fibers, woven negative refractive index cloths, and super-resolving lenses.

Metamaterials at terahertz frequencies offer unique opportunities, but are challenging to fabricate in bulk. We adapt the fabrication procedure for microstructured polymer optical fibers to inexpensively fabricate metamaterials potentially on an industrial scale. We produce polymethylmethacrylate fibers containing ~10 &mu;m diameter indium wires separated by ~100 &mu;m, which exhibit a terahertz plasmonic response.

Metamateriali Realizzazione tramite il metodo di disegno fibra

Metamaterials are man-made composite materials, fabricated by assembling components much smaller than the wavelength at which they operate 1. They owe ...

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

Optical modes of dielectric micro-cavities have received significant attention in recent years for their potential in a broad range of applications. The optical modes are frequently referred to as "whispering gallery modes" (WGM) or "morphology dependent resonances" (MDR) and exhibit high optical quality factors. Some proposed applications of micro-cavity optical resonators are in spectroscopy1, micro-cavity laser technology2, optical communications3-6 as well as sensor technology. The WGM-based sensor applications include those in biology7, trace gas detection8, and impurity detection in liquids9. Mechanical sensors based on microsphere resonators have also been proposed, including those for force10,11, pressure12, acceleration13 and wall shear stress14. In the present, we demonstrate a WGM-based electric field sensor, which builds on our previous studies15,16. A candidate application of this sensor is in the detection of neuronal action potential.
The electric field sensor is based on polymeric multi-layered dielectric microspheres. The external electric field induces surface and body forces on the spheres (electrostriction effect) leading to elastic deformation. This change in the morphology of the spheres, leads to shifts in the WGM. The electric field-induced WGM shifts are interrogated by exciting the optical modes of the spheres by laser light. Light from a distributed feedback (DFB) laser (nominal wavelength of ~ 1.3 &mu;m) is side-coupled into the microspheres using a tapered section of a single mode optical fiber. The base material of the spheres is polydimethylsiloxane (PDMS). Three microsphere geometries are used: (1) PDMS sphere with a 60:1 volumetric ratio of base-to-curing agent mixture, (2) multi layer sphere with 60:1 PDMS core, in order to increase the dielectric constant of the sphere, a middle layer of 60:1 PDMS that is mixed with varying amounts (2% to 10% by volume) of barium titanate and an outer layer of 60:1 PDMS and (3) solid silica sphere coated with a thin layer of uncured PDMS base. In each type of sensor, laser light from the tapered fiber is coupled into the outermost layer that provides high optical quality factor WGM (Q ~ 106). The microspheres are poled for several hours at electric fields of ~ 1 MV/m to increase their sensitivity to electric field.

A high-sensitivity photonic micro sensor was developed for electric field detection. The sensor exploits the optical modes of a dielectric sphere. Changes in the external electric field perturb the sphere morphology leading to shifts in its optical modes. The electric field strength is measured by monitoring these optical shifts.

Sviluppo di Whispering Galleria polimerici modalità micro-ottici sensori di campo elettrico

Optical modes of dielectric micro-cavities have received significant attention in recent years for their potential in a broad range of applications. The ...

Microwave Photonics Systems Based on Whispering-gallery-mode Resonators

Microwave photonics systems rely fundamentally on the interaction between microwave and optical signals. These systems are extremely promising for various areas of technology and applied science, such as aerospace and communication engineering, sensing, metrology, nonlinear photonics, and quantum optics. In this article, we present the principal techniques used in our lab to build microwave photonics systems based on ultra-high Q whispering gallery mode resonators. First detailed in this article is the protocol for resonator polishing, which is based on a grind-and-polish technique close to the ones used to polish optical components such as lenses or telescope mirrors. Then, a white light interferometric profilometer measures surface roughness, which is a key parameter to characterize the quality of the polishing. In order to launch light in the resonator, a tapered silica fiber with diameter in the micrometer range is used. To reach such small diameters, we adopt the "flame-brushing" technique, using simultaneously computer-controlled motors to pull the fiber apart, and a blowtorch to heat the fiber area to be tapered. The resonator and the tapered fiber are later approached to one another to visualize the resonance signal of the whispering gallery modes using a wavelength-scanning laser. By increasing the optical power in the resonator, nonlinear phenomena are triggered until the formation of a Kerr optical frequency comb is observed with a spectrum made of equidistant spectral lines. These Kerr comb spectra have exceptional characteristics that are suitable for several applications in science and technology. We consider the application related to ultra-stable microwave frequency synthesis and demonstrate the generation of a Kerr comb with GHz intermodal frequency.

The customized techniques developed in our lab to build microwave photonics systems based on ultra-high Q whispering gallery mode resonators are presented. The protocols to obtain and characterize these resonators are detailed, and an explanation of some of their applications in microwave photonics is given.

Microonde Photonics sistemi basati su risonatori-galleria-mode Whispering

Microwave photonics systems rely fundamentally on the interaction between microwave and optical signals. These systems are extremely promising for various ...

Fabrication and Characterization of Disordered Polymer Optical Fibers for Transverse Anderson Localization of Light

We develop and characterize a disordered polymer optical fiber that uses transverse Anderson localization as a novel waveguiding mechanism. The developed polymer optical fiber is composed of 80,000 strands of poly (methyl methacrylate) (PMMA) and polystyrene (PS) that are randomly mixed and drawn into a square cross section optical fiber with a side width of 250 &mu;m. Initially, each strand is 200 &mu;m in diameter and 8-inches long. During the mixing process of the original fiber strands, the fibers cross over each other; however, a large draw ratio guarantees that the refractive index profile is invariant along the length of the fiber for several tens of centimeters. The large refractive index difference of 0.1 between the disordered sites results in a small localized beam radius that is comparable to the beam radius of conventional optical fibers. The input light is launched from a standard single mode optical fiber using the butt-coupling method and the near-field output beam from the disordered fiber is imaged using a 40X objective and a CCD camera. The output beam diameter agrees well with the expected results from the numerical simulations. The disordered optical fiber presented in this work is the first device-level implementation of 2D Anderson localization, and can potentially be used for image transport and short-haul optical communication systems.

We develop and characterize a disordered polymer optical fiber that uses transverse Anderson localization as a novel waveguiding mechanism. This microstructured fiber can transport a small localized beam with a radius that is comparable to the beam radius of conventional optical fibers.

Fabbricazione e caratterizzazione di polimeri disordinati fibre ottiche per la Trasversale localizzazione di Anderson di Luce

We develop and characterize a disordered polymer optical fiber that uses transverse Anderson localization as a novel waveguiding mechanism. The developed ...

Fabrication and Testing of Microfluidic Optomechanical Oscillators

Cavity optomechanics experiments that parametrically couple the phonon modes and photon modes have been investigated in various optical systems including microresonators. However, because of the increased acoustic radiative losses during direct liquid immersion of optomechanical devices, almost all published optomechanical experiments have been performed in solid phase. This paper discusses a recently introduced hollow microfluidic optomechanical resonator. Detailed methodology is provided to fabricate these ultra-high-Q microfluidic resonators, perform optomechanical testing, and measure radiation pressure-driven breathing mode and SBS-driven whispering gallery mode parametric vibrations. By confining liquids inside the capillary resonator, high mechanical- and optical- quality factors are simultaneously maintained.

Parametric optomechanical excitations have recently been experimentally demonstrated in microfluidic optomechanical resonators by means of optical radiation pressure and stimulated Brillouin scattering. This paper describes the fabrication of these microfluidic resonators along with methodologies for generating and verifying optomechanical oscillations.

Fabbricazione e la sperimentazione di microfluidici optomechanical Oscillatori

Cavity optomechanics experiments that parametrically couple the phonon modes and photon modes have been investigated in various optical systems including ...

Stimulated Stokes and Antistokes Raman Scattering in Microspherical Whispering Gallery Mode Resonators

Dielectric microspheres can confine light and sound for a length of time through high quality factor whispering gallery modes (WGM). Glass microspheres can be thought as a store of energy with a huge variety of applications: compact laser sources, highly sensitive biochemical sensors and nonlinear phenomena. A protocol for the fabrication of both the microspheres and coupling system is given. The couplers described here are tapered fibers. Efficient generation of nonlinear phenomena related to third order optical non-linear susceptibility &#935;(3) interactions in triply resonant silica microspheres is presented in this paper. The interactions here reported are: Stimulated Raman Scattering (SRS), and four wave mixing processes comprising Stimulated Anti-stokes Raman Scattering (SARS). A proof of the cavity-enhanced phenomenon is given by the lack of correlation among the pump, signal and idler: a resonant mode has to exist in order to obtain the pair of signal and idler. In the case of hyperparametric oscillations (four wave mixing and stimulated anti-stokes Raman scattering), the modes must fulfill the energy and momentum conservation and, last but not least, have a good spatial overlap.

Efficient generation of nonlinear phenomena related to third order optical non-linear susceptibility &#935;(3) interactions in triply resonant silica microspheres is presented in this paper. The interactions here reported are: Stimulated Raman Scattering (SRS), and four wave mixing processes comprising Stimulated Anti-stokes Raman Scattering (SARS).

Stimolata Stokes e Antistokes Raman Scattering in Microspherical Whispering Gallery modalità risonatori

Dielectric microspheres can confine light and sound for a length of time through high quality factor whispering gallery modes (WGM). Glass microspheres ...

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

A &#8220;sheath&#8221; fluid passing through a microfluidic channel at low Reynolds number can be directed around another &#8220;core&#8221; stream and used to dictate the shape as well as the diameter of a core stream.&#160;Grooves in the top and bottom of a microfluidic channel were designed to direct the sheath fluid and shape the core fluid.&#160;By matching the viscosity and hydrophilicity of the sheath and core fluids, the interfacial effects are minimized and complex fluid shapes can be formed.&#160;Controlling the relative flow rates of the sheath and core fluids determines the cross-sectional area of the core fluid.&#160;Fibers have been produced with sizes ranging from 300 nm to ~1 mm, and fiber cross-sections can be round, flat, square, or complex as in the case with double anchor fibers. Polymerization of the core fluid downstream from the shaping region solidifies the fibers.&#160;Photoinitiated click chemistries are well suited for rapid polymerization of the core fluid by irradiation with ultraviolet light.&#160;Fibers with a wide variety of shapes have been produced from a list of polymers including liquid crystals, poly(methylmethacrylate), thiol-ene and thiol-yne resins, polyethylene glycol, and hydrogel derivatives. Minimal shear during the shaping process and mild polymerization conditions also makes the fabrication process well suited for encapsulation of cells and other biological components.

Two adjacent fluids passing through a grooved microfluidic channel can be directed to form a sheath around a prepolymer core; thereby&#160;determining both shape and cross-section. Photoinitiated polymerization, such as thiol click chemistry, is well suited for rapidly solidifying the core fluid into a microfiber with predetermined size and shape.

Fabbricazione microfluidica di fibre polimeriche e bioibride con dimensioni e forma predesignate

A &#8220;sheath&#8221; fluid passing through a microfluidic channel at low Reynolds number can be directed around another &#8220;core&#8221; stream and ...

Bioingegneria

Fabrication of 1-D Photonic Crystal Cavity on a Nanofiber Using Femtosecond Laser-induced Ablation

We present a protocol for fabricating 1-D Photonic Crystal (PhC) cavities on subwavelength-diameter tapered optical fibers, optical nanofibers, using femtosecond laser-induced ablation. We show that thousands of periodic nano-craters are fabricated on an optical nanofiber by irradiating with just a single femtosecond laser pulse. For a typical sample, periodic nano-craters with a period of 350 nm and with diameter gradually varying from 50 - 250 nm over a length of 1 mm are fabricated on a nanofiber with diameter around 450 - 550 nm. A key aspect of such a nanofabrication is that the nanofiber itself acts as a cylindrical lens and focuses the femtosecond laser beam on its shadow surface. Moreover, the single-shot fabrication makes it immune to mechanical instabilities and other fabrication imperfections. Such periodic nano-craters on nanofiber, act as a 1-D PhC and enable strong and broadband reflection while maintaining the high transmission out of the stopband. We also present a method to control the profile of the nano-crater array to fabricate apodized and defect-induced PhC cavities on the nanofiber. The strong confinement of the field, both transverse and longitudinal, in the nanofiber-based PhC cavities and the efficient integration to the fiber networks, may open new possibilities for nanophotonic applications and quantum information science.

We present a protocol for fabricating 1-D photonic crystal cavities on subwavelength diameter silica fibers (optical nanofibers) using femtosecond laser-induced ablation.

Fabbricazione di 1-D Photonic cristallo cavità su una nanofibre Utilizzando ablazione laser a femtosecondi-indotta

We present a protocol for fabricating 1-D Photonic Crystal (PhC) cavities on subwavelength-diameter tapered optical fibers, optical nanofibers, using ...

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Droplet-based microfluidics enable the reliable production of homogeneous microspheres in the microfluidic channel, providing controlled size and morphology of the obtained microsphere. A microsphere copolymerized with an acrydite-DNA probe was successfully fabricated. Different methods such as asymmetric PCR, exonuclease digestion, and isolation on streptavidin-coated magnetic beads can be used to synthesize single-stranded DNA (ssDNA). However, these methods cannot efficiently use large amounts of highly purified ssDNA. Here, we describe a microsphere-PCR protocol detailing how ssDNA can be efficiently amplified and separated from dsDNA simply by pipetting from a PCR reaction tube. The amplification of ssDNA can be applied as potential reagents for the DNA microarray and DNA-SELEX (Systematic evolution of ligands by exponential enrichment) processes.

This work provides a method for the fabrication of droplet-based microfluidic platforms and the application of polyacrylamide microspheres for microsphere-PCR amplification. The microsphere-PCR method makes it possible to obtain single-stranded DNA amplicons without separating double-stranded DNA.