Chapter 23
Drugs for Chronic Bowel Disorders
Chronische Darmerkrankungen: Einführung
Chronic bowel disorders are long-term medical conditions affecting the digestive tract, including disorders such as irritable bowel syndrome or IBS and ...
Medikamente zur Behandlung von diarrhö-prädominantem Reizdarmsyndrom
Diarrhea-predominant irritable bowel syndrome or IBS-D, is characterized by chronic abdominal pain and diarrhea.
Effective IBS-D management involves ...
Medikamente zur Behandlung des obstipations-prädominantem Reizdarmsyndroms
Irritable bowel syndrome with constipation or IBS-C, is a recurring digestive disorder characterized by abdominal pain and infrequent bowel movements.
...
Medikamente zur Behandlung von CEDs: Colitis ulcerosa
Ulcerative colitis is characterized by mucosal inflammation of the colon.
The first-line agent, 5-aminosalicylic acid or 5-ASA, inhibits leukotriene and ...
Medikamente zur Behandlung von CEDs mit immunmodulatorischen Wirkstoffen: Morbus Crohn
Crohn's disease is an inflammatory bowel disorder characterized by discontinuous chronic inflammation of the GI tract.
Treatment strategies encompass ...
Medikamente zur Behandlung von CEDs mit Biologika wie Anti-TNF: Morbus Crohn
Tumor necrosis factor, or TNF, a proinflammatory cytokine, exists in soluble or membrane-bound form.
TNF-receptor interaction triggers NF-κB, T-cell ...
Glukokortikoide zur Behandlung von CEDs: Morbus Crohn
Glucocorticoids, like prednisone, are potent anti-inflammatory agents that induce effective remission in Crohn's patients.
These bind and activate ...
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