Tropomodulin 3 Overexpression as a Marker for Platinum Resistance and Immune Infiltration in Ovarian Cancer

2.5K Views

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09:40 min

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August 2nd, 2024

DOI :

10.3791/65841-v

August 2nd, 2024

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Dingwen Xu*¹, Xiaofei Hu*², Yang Feng¹, Zhihua Lu¹, Xianmei Liu³, Huishen Yan¹, Jianming Peng¹, Sen Luo¹, Weijuan Yao⁴

¹Department of Clinic, School of Medicine, Yangzhou Polytechnic College, ²Department of Nuclear Medicine, Huangshi Central Hospital, Affiliated Hospital of Hubei Institute of Technology, ³School of Biology and Engineering, Guizhou Medical University, ⁴Hemorheology Center, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center

Summary

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Gene Expression Omnibus GEO

The Cancer Genome Atlas TCGA

Clinical Proteomic Tumor Analysis Consortium CPTAC

Overall Survival OS

Progression free Survival PFS

MicroRNAs miRNAs

Immune Infiltration Analysis

Coexpression Networks

Chapters in this video

0:00

Introduction

0:51

Analyzing the Expression of TMOD3 in Normal Ovarian Tissues and Ovarian Cancer

2:23

Assessing the Effect of TMOD3 on Overall Survival and Progression‐Free Survival (PFS) in Ovarian Cancer Patients

4:15

TMOD3 Expression Analysis in Platinum‐Based Chemotherapy Resistant and Sensitive Patients and mRNA‐miRNA Analysis

6:56

Checking the Distribution of TMOD3 in Immune Cells and TMOD3 Coexpression Networks in Ovarian Cancer

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