Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis
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06:09 min
•
February 2nd, 2021
DOI :
February 2nd, 2021
•Darren M. O'Hara1,2, Minesh Kapadia1,2, Susan Ping1,2, Suneil K. Kalia1,2,3, Lorraine V. Kalia1,2,4,5,6
1Krembil Research Institute, Toronto Western Hospital, University Health Network, 2Department of Laboratory Medicine and Pathobiology, University of Toronto, 3Department of Surgery, Division of Neurosurgery, University of Toronto, 4Department of Medicine, Division of Neurology, University of Toronto, 5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, 6Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
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Chapters in this video
0:04
Introduction
0:50
Confocal Microscopy and Image Acquisition
2:43
Image Analysis and Quantitation
4:33
Results: Quantitation of Dopaminergic Neuron Density in Brain Sections Using Automated Image Analysis
5:20
Conclusion
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