Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry
5.1K Views
•
10:58 min
•
September 27th, 2020
DOI :
September 27th, 2020
•Wilson Wang*1, Yanrong Zhang*2, Matthew J. Anzivino1, Edward H. Bertram3, James Woznak1,4, Alexander Klibanov5, Erik Dumont6, Max Wintermark*2, Kevin S. Lee*1,7,8
1Department of Neuroscience, University of Virginia, 2Department of Radiology, Stanford University, 3Department of Neurology, University of Virginia, 4Global Internship Program, Focused Ultrasound Foundation, 5Department of Medicine, University of Virginia, 6Image Guided Therapy, 7Department of Neurosurgery, University of Virginia, 8Center for Brain, Immunology, and Glia, University of Virginia
Explore More Videos
Chapters in this video
0:00
Introduction
1:36
Animal Preparation
2:44
PING Procedure
5:55
MRI/FUS Control Room
6:35
Targeting of FUS
7:07
Administration of Microbubble, FUS, and Contrast Age
7:47
Infusion of Quinolinic Acid
8:15
Results: Imaging and Microscopy
10:03
Conclusions for PING Method
Related Videos
06:33
The Organotypic Hippocampal Slice Culture Model for Examining Neuronal Injury
19.0K Views
16:16
Membrane Potentials, Synaptic Responses, Neuronal Circuitry, Neuromodulation and Muscle Histology Using the Crayfish: Student Laboratory Exercises
58.8K Views
09:07
Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
13.6K Views
12:00
Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
12.1K Views
08:21
Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries
7.1K Views
00:08
Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity
13.3K Views
08:26
Non-Invasive Modulation and Robotic Mapping of Motor Cortex in the Developing Brain
6.7K Views
08:51
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
5.6K Views
07:05
Laser-Induced Brain Injury in the Motor Cortex of Rats
5.2K Views
14:53
Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
10.2K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved