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Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques

11.3K Views

10:52 min

June 1st, 2016

DOI :

10.3791/54060-v

June 1st, 2016


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Correlative Light And Electron Microscopy

Chapters in this video

0:05

Title

0:57

Methoxy-X04 Solution Preparation and Injection

1:52

Brain Sectioning Using a Vibratome

3:21

Screening for the Presence of Methoxy-X04-stained Plaques

5:40

Tissue Processing for Electron Microscopy

9:01

Results: Visualization of Aβ Plaques in 21-month-old APP-PS1 Mice Using Light Microscopy Following Systemic Injection of the Fluorescent Dye Methoxy-X04

10:01

Conclusion

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