Robert A. Anders

Rosai-Dorfman disease presenting in the gastrointestinal tract.

cDNA microarray analysis of macroregenerative and dysplastic nodules in end-stage hepatitis C virus-induced cirrhosis.

Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection.

Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy.

Caveolin and thrombospondin expression during hepatocellular carcinogenesis.

The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses.

The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.

Contribution of the lymphotoxin beta receptor to liver regeneration.

Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma.

Glycogen pseudoground glass change in hepatocytes.

Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.

Preoperative assessment of hepatocellular carcinoma tumor grade using needle biopsy: implications for transplant eligibility.

Biopsy considerations in the diagnosis of hepatic masses.

Hepatotoxicity associated with dietary supplements containing anabolic steroids.

Elucidation of a universal size-control mechanism in Drosophila and mammals.

The hippo pathway in human upper gastrointestinal dysplasia and carcinoma: a novel oncogenic pathway.

Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.

Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling.

Expression of Yes-associated protein in common solid tumors.

T cell-derived lymphotoxin regulates liver regeneration.

Metastatic renal cell carcinoma within a hepatic focal nodular hyperplasia: a case report and review of the literature.

Hepatitis in common variable immunodeficiency.

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.

Immunostaining of plasma cells in primary biliary cirrhosis.

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin.

Johns Hopkins course: 8th annual Current Topics in Gastrointestinal and Liver Pathology.

Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.

Depth of tumor invasion better predicts prognosis than the current American Joint Committee on Cancer T classification for distal bile duct carcinoma.

Tc17 CD8 T cells: functional plasticity and subset diversity.

Genomic and immunophenotypical differences between hepatocellular carcinoma with and without cirrhosis.

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.

Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms.

Autoimmune hepatitis in patients with primary Sjögren's syndrome: a series of two-hundred and two patients.

Hepatocellular carcinoma in a teenager with perinatally acquired HIV Infection without hepatitis B or C coinfection: a case report.

Variation in lymph node assessment after colon cancer resection: patient, surgeon, pathologist, or hospital?

The role of liver-directed surgery in patients with hepatic metastasis from a gynecologic primary carcinoma.

Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia.

Hyperplastic Luschka ducts: a mimic of adenocarcinoma in the gallbladder fossa.

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth.

Refining the definition of perioperative mortality following hepatectomy using death within 90 days as the standard criterion.

Hilar cholangiocarcinoma: tumor depth as a predictor of outcome.

A polymeric nanoparticle formulation of curcumin (NanoCurcâ„¢) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

Shifting trends in liver-directed management of patients with colorectal liver metastasis: a population-based analysis.

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma.

A Polymeric Nanoparticle Encapsulated Hedgehog Pathway Inhibitor HPI-1 (NanoHHI) Inhibits Systemic Metastases in an Orthotopic Model of Human Hepatocellular Carcinoma.

Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver.

Sarcina organisms in the gastrointestinal tract: a clinicopathologic and molecular study.

Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.

Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape.

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.

Yes-associated protein regulates the hepatic response after bile duct ligation.

Durable Cancer Regression Off-treatment and Effective Re-induction Therapy with an Anti-PD-1 Antibody.

HIF-2α inhibits hepatocellular carcinoma growth through the TFDP3/E2F1-dependent apoptotic pathway.

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints.

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome.

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas.

Treatment and prognosis of patients with fibrolamellar hepatocellular carcinoma: a national perspective.

Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection.

PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival.

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy.

The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease.

Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.

Temporal trends in population-based death rates associated with chronic liver disease and liver cancer in the United States over the last 30 years.

Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation.

The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy.

PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation.

Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo.

PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors.

Pharmacological activation of myosin II paralogs to correct cell mechanics defects.

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis.

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer.

Rotavirus Infects Human Biliary Epithelial Cells and Stimulates Secretion of Cytokines IL-6 and IL-8 via MAPK Pathway.

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution.

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.

A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma.

PD-L1 Expression as a Predictive Biomarker: Is Absence of Proof the Same as Proof of Absence?

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma.

Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma.

Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer.

Ganetespib radiosensitization for liver cancer therapy.

Program Death 1 Immune Checkpoint and Tumor Microenvironment: Implications for Patients With Intrahepatic Cholangiocarcinoma.

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy.

Magnetoencapsulated human islets xenotransplanted into swine: a comparison of different transplantation sites.

Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization.

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma.

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015.

The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated with Anti-PD-1 Response in Patients with Renal Cell Carcinoma.

Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.

Emerging role of Hpo signaling and YAP in hepatocellular carcinoma.

Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.

Microvascular Invasion in Hepatocellular Carcinoma and Liver Transplant.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors.

PBRM1 loss is a late event during the development of cholangiocarcinoma.

PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison.

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

Melanoma subtypes demonstrate distinct PD-L1 expression profiles.

Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment.

Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.

Derivation of a disease-specific human induced pluripotent stem cell line from a biliary atresia patient.

Distinction of intrahepatic metastasis from multicentric carcinogenesis in multifocal hepatocellular carcinoma using molecular alterations.

Implications of the tumor immune microenvironment for staging and therapeutics.

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.

Th17 immune microenvironment in Epstein-Barr virus-negative Hodgkin lymphoma: implications for immunotherapy.

PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.

Prediction of post-TACE necrosis of hepatocellular carcinoma usingvolumetric enhancement on MRI and volumetric oil deposition on CT, with pathological correlation.

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria.

Histopathological and immunophenotypic features of ipilimumab-associated colitis compared to ulcerative colitis.

Impact of histological subtype on the prognosis of patients undergoing surgery for colon cancer.

Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy.

Bariatric Arterial Embolization: Effect of Microsphere Size on the Suppression of Fundal Ghrelin Expression and Weight Change in a Swine Model.

Accuracy of Milan, University of California San Francisco, and Up-To-7 Criteria in Predicting Tumor Recurrence Following Deceased-Donor Liver Transplant in Patients With Hepatocellular Carcinoma.

Stem Cell Mobilization Is Lifesaving in a Large Animal Preclinical Model of Acute Liver Failure.

Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab.

Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors.

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.

Multiple Immune-Suppressive Mechanisms in Fibrolamellar Carcinoma.

Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors.

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice.

Clinicopathological Distinction of Low-AFP-Secreting vs. High-AFP-Secreting Hepatocellular Carcinomas.

Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade: A Systematic Review and Meta-analysis.

Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14.

Abundant Expression of Lysyl Oxidase-like 2 Protein in Intrahepatic Bile Ducts of Infants With Biliary Atresia.

Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy.

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.

Pan-Tumor Pathologic Scoring of Response to PD-(L)1 Blockade.

The number of microspheres in Y90 radioembolization directly affects normal tissue radiation exposure.

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer.

Role of baseline volumetric functional MRI in predicting histopathologic grade and patients' survival in hepatocellular carcinoma.

Evaluation of Cyclophosphamide/GVAX Pancreas Followed by Listeria-Mesothelin (CRS-207) with or without Nivolumab in Patients with Pancreatic Cancer.

The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures.

Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development.

A Phase II Study of Allogeneic GM-CSF-Transfected Pancreatic Tumor Vaccine (GVAX) with Ipilimumab as Maintenance Treatment for Metastatic Pancreatic Cancer.

Bariatric Arterial Embolization with Calibrated Radiopaque Microspheres and an Antireflux Catheter Suppresses Weight Gain and Appetite-Stimulating Hormones in Swine.

The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma.

Vaccine-Induced Intratumoral Lymphoid Aggregates Correlate with Survival Following Treatment with a Neoadjuvant and Adjuvant Vaccine in Patients with Resectable Pancreatic Adenocarcinoma.

A feasibility study of combined epigenetic and vaccine therapy in advanced colorectal cancer with pharmacodynamic endpoint.

Bacterial-Driven Inflammation and Mutant Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.

Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms.

Development, Practice Patterns, and Early Clinical Outcomes of a Multidisciplinary Liver Cancer Clinic.

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis.

A Novel NIPBL-NACC1 Gene Fusion Is Characteristic of the Cholangioblastic Variant of Intrahepatic Cholangiocarcinoma.

Prognostic Implications of the Immune Tumor Microenvironment in Patients With Pancreatic and Gastrointestinal Neuroendocrine Tumors.

Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade.

Evaluation of Early vs Standard Liver Transplant for Alcohol-Associated Liver Disease.

Spatial UMAP and Image Cytometry for Topographic Immuno-oncology Biomarker Discovery.

Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8 T-Cell Infiltration After Heart Transplantation.

PD-L1 (Programmed Death Ligand 1) as a Marker of Acute Cellular Rejection After Heart Transplantation.

Neoadjuvant Cabozantinib and Nivolumab Converts Locally Advanced HCC into Resectable Disease with Enhanced Antitumor Immunity.

Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers.

Identifying the Ideal Target Vessel Size for Bariatric Embolization: Histologic Analysis of Swine and Human Gastric Fundi.

Liver Transplant in Hemoglobin SC Disease and Autoimmune Hepatitis: A Case Report.

Pancreatic Ductal Adenocarcinoma Cortical Mechanics and Clinical Implications.

Expanding the immunotherapy roadmap for hepatocellular carcinoma.

Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses.

Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer.

Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy.

Detecting Liver Cancer Using Cell-Free DNA Fragmentomes.

Generation and multiomic profiling of a double-knockout gastroesophageal junction organoid model.

Impact of the COVID-19 Pandemic on Liver Cancer Staging at a Multidisciplinary Liver Cancer Clinic.

Digital imaging software versus the "eyeball" method in quantifying steatosis in a liver biopsy.

Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.

Multi-Institutional Study of Pathologist Reading of the Programmed Cell Death Ligand-1 Combined Positive Score Immunohistochemistry Assay for Gastric or Gastroesophageal Junction Cancer.

Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces.

Erratum to High Interobserver Variability Among Pathologists Using Combined Positive Score to Evaluate PD-L1 Expression in Gastric, Gastroesophageal Junction, and Esophageal Adenocarcinoma [Modern Pathology 36(5) (2023) 100154].

Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial.

Balancing Safety and Efficacy to Determine the Most Suitable Size of Imaging-Visible Embolic Microspheres for Bariatric Arterial Embolization in a Preclinical Model.

Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.

Association between pathologic response and survival after neoadjuvant therapy in lung cancer.

Neoadjuvant radioimmunotherapy in pancreatic cancer enhances effector T cell infiltration and shortens their distances to tumor cells.

Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade.

Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery.

Impact of Neoadjuvant Immunotherapy on Recurrence-Free Survival in Patients with High-Risk Localized HCC.

SREBP-Dependent Regulation of Lipid Homeostasis Is Required for Progression and Growth of Pancreatic Ductal Adenocarcinoma.

Multidimensional Immunotyping of Human NF1-Associated Peripheral Nerve Sheath Tumors Uncovers Tumor-Associated Macrophages as Key Drivers of Immune Evasion in the Tumor Microenvironment.

Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma.

Concordance of Whole-Slide Imaging and Conventional Light Microscopy for Assessment of Pathologic Response Following Neoadjuvant Therapy for Lung Cancer.

Highly Multiplexed Immunofluorescence PhenoCycler Panel for Murine Formalin-Fixed Paraffin-Embedded Tissues Yields Insight Into Tumor Microenvironment Immunoengineering.

Immune microenvironment of Epstein-Barr virus (EBV)-negative compared to EBV-associated gastric cancers: implications for immunotherapy.

CD137 agonism enhances anti-PD1 induced activation of expanded CD8 T cell clones in a neoadjuvant pancreatic cancer clinical trial.

Cholangioblastic Cholangiocarcinoma ( NIPBL :: NACC1 Cholangiocarcinoma) : Expanded Morphologic Spectrum and Further Genetic Characterization.

A phase II study of neoadjuvant GVAX and cyclophosphamide combined with nivolumab and SBRT followed by surgery in borderline resectable pancreatic adenocarcinoma.