Ana D. Lopez

Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells.

A novel approach to increase human islet cell mass while preserving beta-cell function.

Maintenance of pluripotency in human embryonic stem cells is STAT3 independent.

Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers.

Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells.

Generation of definitive endoderm from human embryonic stem cells cultured in feeder layer-free conditions.

The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells.

sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveal differentially expressed microRNAs and novel isomiRs with distinct targets.