Capítulo 12
Estrutura e componentes da membrana
O que são Membranas?
A cell's plasma membrane demarcates the cell's borders and determines the nature of its interaction with the environment. Cells exclude certain ...
Fluidez de Membrana
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of ...
Modelo do Mosaico Fluido
Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane ...
Lipídios de Membrana
Lipids are an essential component of all biological membranes. The average lipid content in mammalian membranes is 50%, though it can be as low as 20% in ...
Bicamana Lipídica Assimétrica
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. ...
Transportadores Reguladores de Assimetria de Membrana
Enzymes like flippase, floppase, and scramblase transfer phospholipids from one layer to another in the membrane, thereby affecting membrane asymmetry.
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Carboidratos de Membrana
The plasma membrane is a dynamic barrier composed of lipids, proteins, and carbohydrates. It is the epicenter of many cellular processes required for cell ...
Proteínas de Membrana
Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport ...
Lípidos como Âncoras
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors ...
Proteínas Transmembranares de Passagem Única
Integral membrane proteins are tightly associated with the cell membrane and play a crucial role in cell communication, signaling, adhesion, and transport ...
Proteínas Transmembrana de Multiplas Passagens e Barris-β
In multi-pass transmembrane proteins, the polypeptide chain crosses the membrane more than once. The transmembrane polypeptide chain either forms an ...
Purificação de Proteínas de Membrana com Detergente
Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while ...
Difusão de Proteínas na Membrana
Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion ...
Domínios de Membrana
The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other ...
Mecanismos de Formação de Domínios da Membrana
Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains ...
Mecanismos de Curvatura de Membranas
The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by ...
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