A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Please note that all translations are automatically generated. Click here for the English version.
2.3K Views
•
12:21 min
•
September 28th, 2022
DOI :
September 28th, 2022
•Alexsandra Lenhard*1, Basma H. Joma*2,3, Nalat Siwapornchai2, Anders P. Hakansson4, John M. Leong2,5, Elsa N. Bou Ghanem1
1Department of Microbiology and Immunology, University at Buffalo School of Medicine, 2Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 3Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, 4Department of Translational Medicine, Lund University, 5Stuart B. Levy Center for the Integrated Management of Antimicrobial Resistance, Tufts University
Rozdziały w tym wideo
0:05
Introduction
0:55
Growing Streptococcus pneumoniae Biofilm
4:15
Intranasal Inoculation of Mice with Biofilm-Grown S. pneumoniae
5:11
Viral Infection with Influenza A Virus (IAV)
6:01
Processing of Infected Tissues for Bacterial Enumeration
8:35
Processing of the Lung Samples for Flow Cytometry
9:07
Results: Enhancement of S. pneumoniae Pathogenicity upon Viral Infection and Advanced Age
11:43
Conclusion
Powiązane Filmy
11:04
The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis
26.3K Views
13:54
Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
10.4K Views
09:12
Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
12.3K Views
11:40
Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
14.8K Views
11:32
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
15.0K Views
09:52
A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
17.5K Views
06:43
Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
8.4K Views
07:43
A Non-invasive and Technically Non-intensive Method for Induction and Phenotyping of Experimental Bacterial Pneumonia in Mice
8.9K Views
08:25
Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
8.9K Views
04:32
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
11.6K Views
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone