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A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

10.1K Views

11:15 min

May 6th, 2018

DOI :

10.3791/56932-v

May 6th, 2018


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Preclinical Mouse Model

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0:04

Title

1:20

Isolation of Tumor-secreted Extracellular Vesicles (EVs)

4:00

Generation of an Orthotopic Xenograft Mouse Model of Osteosarcoma

6:44

Assessment of Lung Nodule Number

7:57

Histological Analysis of GFP-positive MSCs in Mouse Tibias

8:53

Results: Analysis of Mice Injected with EV-educated MSCs

10:31

Conclusion

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