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Chapter 23
Chronic bowel disorders are long-term medical conditions affecting the digestive tract, including disorders such as irritable bowel syndrome or IBS and ...
Diarrhea-predominant irritable bowel syndrome or IBS-D, is characterized by chronic abdominal pain and diarrhea. Effective IBS-D management involves ...
Irritable bowel syndrome with constipation or IBS-C, is a recurring digestive disorder characterized by abdominal pain and infrequent bowel movements. ...
Ulcerative colitis is characterized by mucosal inflammation of the colon. The first-line agent, 5-aminosalicylic acid or 5-ASA, inhibits leukotriene and ...
Crohn's disease is an inflammatory bowel disorder characterized by discontinuous chronic inflammation of the GI tract. Treatment strategies encompass ...
Tumor necrosis factor, or TNF, a proinflammatory cytokine, exists in soluble or membrane-bound form. TNF-receptor interaction triggers NF-κB, T-cell ...
Glucocorticoids, like prednisone, are potent anti-inflammatory agents that induce effective remission in Crohn's patients. These bind and activate ...
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