Gaya Amarasinghe

Molecular mechanisms of viral inhibitors of RIG-I-like receptors.

Aptamers in virology: recent advances and challenges.

Structural insights into RNA recognition and activation of RIG-I-like receptors.

Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.

An upstream open reading frame modulates ebola virus polymerase translation and virus replication.

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

Development of RNA aptamers targeting Ebola virus VP35.

A calcium-fortified viral matrix protein.

A viral RNA structural element alters host recognition of nonself RNA.

In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.

The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway.

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis.

Defining a two-pronged structural model for PB1 (Phox/Bem1p) domain interaction in plant auxin responses.

An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

When your cap matters: structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins.

Taxonomy of the order Mononegavirales: update 2016.

Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.

Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses.

Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials.

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability.

A Sensitive in Vitro High-Throughput Screen To Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface.

Taxonomy of the order Mononegavirales: update 2017.

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses.

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses.

Filovirus Strategies to Escape Antiviral Responses.

Filovirus Structural Biology: The Molecules in the Machine.

Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.

Nucleotide resolution mapping of influenza A virus nucleoprotein-RNA interactions reveals RNA features required for replication.

Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.

LysMD3 is a type II membrane protein without an role in the response to a range of pathogens.

Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.

Taxonomy of the order Mononegavirales: update 2018.

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.

Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms.

MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.

Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Applications of Parametrized NMR Spin Systems of Small Molecules.

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.

Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets.

Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities.

Taxonomy of the order Mononegavirales: second update 2018.

Potent Neutralization of Staphylococcal Enterotoxin B In Vivo by Antibodies that Block Binding to the T-Cell Receptor.

Backbone resonance assignments and secondary structure of Ebola nucleoprotein 600-739 construct.

Taxonomy of the order Mononegavirales: update 2019.

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.

Ebola Virus Replication Stands Out.

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription.

Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner.

The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target.

Fragment screening targeting Ebola virus nucleoprotein C-terminal domain identifies lead candidates.

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2.

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain.

Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2.

Itaconate confers tolerance to late NLRP3 inflammasome activation.

Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain.

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

Lrp1 is a host entry factor for Rift Valley fever virus.

Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein.

Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription.

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong.

Cryo-EM analysis of Ebola virus nucleocapsid-like assembly.

Nipah Virus V Protein Binding Alters MDA5 Helicase Folding Dynamics.

Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins.

A cryptic pocket in Ebola VP35 allosterically controls RNA binding.

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies.

Ultrapotent and broad neutralization of SARS-CoV-2 variants by modular, tetravalent, bi-paratopic antibodies.

SARS-CoV-2 accessory proteins reveal distinct serological signatures in children.

Liquid Phase Partitioning in Virus Replication: Observations and Opportunities.

Peptide-Antibody Fusions Engineered by Phage Display Exhibit an Ultrapotent and Broad Neutralization of SARS-CoV-2 Variants.

LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.

Rapid detection of an Ebola biomarker with optical microring resonators.

Monoclonal antibodies binding data for SARS-CoV-2 proteins.

The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.

Plasmonic Fluor-Enhanced Antigen Arrays for High-Throughput, Serological Studies of SARS-CoV-2.

Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.

Detection of biomarkers for filoviral infection with a silicon photonic resonator platform.

Rift Valley Fever Virus Infects the Posterior Segment of the Eye and Induces Inflammation in a Rat Model of Ocular Disease.

Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.

Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population.

Biochemical and HDX Mass Spectral Characterization of the SARS-CoV-2 Nsp1 Protein.

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24.

Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice.

Disruption of Ebola NPVP35 Inclusion Body-like Structures reduce Viral Infection.

Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes.

Host entry factors of Rift Valley Fever Virus infection.

Author Correction: Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population.

A Flexible, Quantitative Plasmonic-Fluor Lateral Flow Assay for the Rapid Detection of and .

Serological assays for differentiating natural COVID-19 infection from vaccine induced immunity.

Viral Targeting of Importin Alpha-Mediated Nuclear Import to Block Innate Immunity.

Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics.

Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination.

Characterization of neural infection by Oropouche orthobunyavirus.

Lrp1 facilitates infection of neurons by Jamestown Canyon virus.

Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25.