Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat ModelWanqing Ren *1, Tongzheng Liu *2, Jie Liu 3, Jianlin Wu 1
1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, 2Innovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, 3Office of Shandong College of Traditional Chinese Medicine
This study evaluated the antidepressant efficacy of Qiangzhifang in a rat model of chronic restraint stress-induced depression and elucidated its regulatory effect on HIF-1 and JAK-STAT pathways by network pharmacology and molecular docking analysis.
