Cell Therapy Center,
Beijing Institute of Geriatrics,
Xuanwu Hospital,
Capital Medical University,
and Key Laboratory of Neurodegeneration,
Cell Therapy Center, Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, and Key Laboratory of Neurodegeneration
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Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis.
International journal of cancer Jan, 2010 | Pubmed ID: 19521958
Cancer/testis antigens and clinical risk factors for liver metastasis of colorectal cancer: a predictive panel.
Diseases of the colon and rectum Jan, 2010 | Pubmed ID: 20010347
Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors.
Cell research Jan, 2012 | Pubmed ID: 22064700
Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors.
Cell research Apr, 2012 | Pubmed ID: 22370632
Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis.
Brain, behavior, and immunity May, 2013 | Pubmed ID: 23402793
Autologous transplantation of GDNF-expressing mesenchymal stem cells protects against MPTP-induced damage in cynomolgus monkeys.
Scientific reports Sep, 2013 | Pubmed ID: 24071770
MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1.
Molecular cancer Apr, 2014 | Pubmed ID: 24755295
Introduction to the special topic "stem cells and regenerative medicine".
Science China. Life sciences Jun, 2014 | Pubmed ID: 24849512
Lmx1a enhances the effect of iNSCs in a PD model.
Stem cell research Jan, 2015 | Pubmed ID: 25460246
Cell therapy for macular degeneration--first phase I/II pluripotent stem cell-based clinical trial shows promise.
Science China. Life sciences Jan, 2015 | Pubmed ID: 25528254
Comparison of intracerebral transplantation effects of different stem cells on rodent stroke models.
Cell biochemistry and function Jun, 2015 | Pubmed ID: 25914321
Cell Therapy for Parkinson's Disease: New Hope from Reprogramming Technologies.
Aging and disease Nov, 2015 | Pubmed ID: 26618051
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.
Nature communications Dec, 2015 | Pubmed ID: 26632666
Conversion of adult human peripheral blood mononuclear cells into induced neural stem cell by using episomal vectors.
Stem cell research Mar, 2016 | Pubmed ID: 26826927
Aberrant trafficking of a Leu89Pro connexin32 mutant associated with X-linked dominant Charcot-Marie-Tooth disease.
Neurological research Oct, 2016 | Pubmed ID: 27367520
Autologous iPSC-derived dopamine neuron transplantation in a nonhuman primate Parkinson's disease model.
Cell discovery , 2015 | Pubmed ID: 27462412
Accelerated generation of oligodendrocyte progenitor cells from human induced pluripotent stem cells by forced expression of Sox10 and Olig2.
Science China. Life sciences Nov, 2016 | Pubmed ID: 27785726
MRI tracking of autologous pancreatic progenitor-derived insulin-producing cells in monkeys.
Scientific reports 05, 2017 | Pubmed ID: 28566744
SIRT6 deficiency results in developmental retardation in cynomolgus monkeys.
Nature 08, 2018 | Pubmed ID: 30135584
Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy.
Frontiers in cellular neuroscience , 2018 | Pubmed ID: 30140204
Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model.
Cell death & disease Sep, 2018 | Pubmed ID: 30206203
Culture of pyramidal neural precursors, neural stem cells, and fibroblasts on various biomaterials.
Journal of biomaterials science. Polymer edition 12, 2018 | Pubmed ID: 30261158
Dopaminergic precursors differentiated from human blood-derived induced neural stem cells improve symptoms of a mouse Parkinson's disease model.
Theranostics , 2018 | Pubmed ID: 30279731
Intravenous Transplantation of Mesenchymal Stem Cells Reduces the Number of Infiltrated Ly6C Cells but Enhances the Proportions Positive for BDNF, TNF-1, and IL-1 in the Infarct Cortices of dMCAO Rats.
Stem cells international , 2018 | Pubmed ID: 30405724
Melatonin Treatment Alleviates Spinal Cord Injury-Induced Gut Dysbiosis in Mice.
Journal of neurotrauma Mar, 2019 | Pubmed ID: 30693824
Employing Endogenous NSCs to Promote Recovery of Spinal Cord Injury.
Stem cells international , 2019 | Pubmed ID: 31191666
BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction.
Cell reports Jan, 2014 | Pubmed ID: 24373973
Overcoming BET Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2019 | Pubmed ID: 30796033
Treatment with Humanized Selective CD19CAR-T Cells Shows Efficacy in Highly Treated B-ALL Patients Who Have Relapsed after Receiving Murine-Based CD19CAR-T Therapies.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2019 | Pubmed ID: 31300451
The Effect of Human Umbilical Cord Mesenchymal Stromal Cells in Protection of Dopaminergic Neurons from Apoptosis by Reducing Oxidative Stress in the Early Stage of a 6-OHDA-Induced Parkinson's Disease Model.
Cell transplantation Dec, 2019 | Pubmed ID: 31775521
Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson's Disease.
Frontiers in cellular neuroscience , 2020 | Pubmed ID: 32210767
Mesenchymal Stem/Stromal Cell-Mediated Mitochondrial Transfer and the Therapeutic Potential in Treatment of Neurological Diseases.
Stem cells international , 2020 | Pubmed ID: 32724315
Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model.
Stem cells international , 2020 | Pubmed ID: 32952570
Unusual electrophysiological findings in a Chinese ALS 4 family with SETX-L389S mutation: a three-year follow-up.
Journal of neurology Mar, 2021 | Pubmed ID: 32997296
Case Report: Humanized Selective CD19CAR-T Treatment Induces MRD-Negative Remission in a Pediatric B-ALL Patient With Primary Resistance to Murine-Based CD19CAR-T Therapy.
Frontiers in immunology , 2020 | Pubmed ID: 33424835
Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis.
Microbiome Mar, 2021 | Pubmed ID: 33678185
Astrocytes constitute the major TNF-α-producing cell population in the infarct cortex in dMCAO rats receiving intravenous MSC infusion.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Oct, 2021 | Pubmed ID: 34343893
Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site.
Microbiology spectrum Jun, 2022 | Pubmed ID: 35467388
Induced neural stem cells from Macaca fascicularis show potential of dopaminergic neuron specification and efficacy in a mouse Parkinson's disease model.
Acta histochemica Aug, 2022 | Pubmed ID: 35792494
Long-Term Safety and Efficacy of CD19 Humanized Selective CAR-T Therapy in B-ALL Patients Who Have Previously Received Murine-Based CD19 CAR-T Therapy.
Frontiers in oncology , 2022 | Pubmed ID: 35800047
Neuroprotective effects of human umbilical cord mesenchymal stromal cells in PD mice via centrally and peripherally suppressing NLRP3 inflammasome-mediated inflammatory responses.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Sep, 2022 | Pubmed ID: 36076517
Characterization of Human-Induced Neural Stem Cells and Derivatives following Transplantation into the Central Nervous System of a Nonhuman Primate and Rats.
Stem cells international , 2022 | Pubmed ID: 36618021
Probiotic Formulation VSL#3 Interacts with Mesenchymal Stromal Cells To Protect Dopaminergic Neurons via Centrally and Peripherally Suppressing NOD-Like Receptor Protein 3 Inflammasome-Mediated Inflammation in Parkinson's Disease Mice.
Microbiology spectrum Feb, 2023 | Pubmed ID: 36728426
GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy.
Translational oncology Jun, 2023 | Pubmed ID: 36966611
MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.
The ocular surface Apr, 2023 | Pubmed ID: 36990276
Human iPSC-derived midbrain organoids functionally integrate into striatum circuits and restore motor function in a mouse model of Parkinson's disease.
Theranostics , 2023 | Pubmed ID: 37215566
Suppression of TGFβR-Smad3 pathway alleviates the syrinx induced by syringomyelia.
Cell & bioscience May, 2023 | Pubmed ID: 37248485
Therapeutic effects against high-grade glioblastoma mediated by engineered induced neural stem cells combined with GD2-specific CAR-NK.
Cellular oncology (Dordrecht, Netherlands) Dec, 2023 | Pubmed ID: 37420122
Human iPSC-derived endothelial cells promote CNS remyelination via BDNF and mTORC1 pathway.
Glia Jan, 2024 | Pubmed ID: 37675625
A C2C3 hinge region enhances the cytotoxicity of anti-CD5 CAR-T cells targeting T cell acute lymphoblastic leukemia.
International immunopharmacology Nov, 2023 | Pubmed ID: 37690234
Human midbrain dopaminergic progenitors.
Cell proliferation Apr, 2024 | Pubmed ID: 37881164
First-in-human transplantation of autologous induced neural stem cell-derived dopaminergic precursors to treat Parkinson's disease.
Science bulletin Nov, 2023 | Pubmed ID: 37919161
Spinal cord injury-induced gut dysbiosis influences neurological recovery partly through short-chain fatty acids.
NPJ biofilms and microbiomes Dec, 2023 | Pubmed ID: 38092763
In vitro differentiation of human CD45 CD34 induced hematopoietic progenitor cells from iPSCs using a monolayer system.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis Feb, 2024 | Pubmed ID: 38182435
Grafted human-induced pluripotent stem cells-derived oligodendrocyte progenitor cells combined with human umbilical vein endothelial cells contribute to functional recovery following spinal cord injury.
Stem cell research & therapy Feb, 2024 | Pubmed ID: 38321505
Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells.
Tissue engineering and regenerative medicine Jun, 2024 | Pubmed ID: 38578425
Human induced pluripotent stem cell/embryonic stem cell-derived pyramidal neuronal precursors show safety and efficacy in a rat spinal cord injury model.
Cellular and molecular life sciences : CMLS Jul, 2024 | Pubmed ID: 39073571
Immune Cells Promote BDNF Expression by Infiltrated Macrophages via Interleukin 4 in the Cerebral Ischemia of Male Rats.
Journal of neuroscience research Sep, 2024 | Pubmed ID: 39235282
Modulation of human induced neural stem cell-derived dopaminergic neurons by DREADD reveals therapeutic effects on a mouse model of Parkinson's disease.
Stem cell research & therapy Sep, 2024 | Pubmed ID: 39256801
The isoflavone puerarin promotes generation of human iPSC-derived pre-oligodendrocytes and enhances endogenous remyelination in rodent models.
Journal of neurochemistry Jan, 2025 | Pubmed ID: 39424593
Robot-Assisted Stereotactic Microinjection Method for Precision Cell Transplantation in Rat and Canine Models.
Cell transplantation , 2025 | Pubmed ID: 40103182
Krystina Rhéaume*,1,
Zhiguo Chen*,2,
Yong Wang*,2,
Camille Plante1,
Dhanushka Hewa Bostanthirige1,
Maude Lévesque1,
Sameh Geha3,4,
Lu Q. Le2,5,6,7,
Jean-Philippe Brosseau1,4
1Department of Biochemistry and Functional Genomics, Université de Sherbrooke,
2Department of Dermatology, University of Texas Southwestern Medical Center at Dallas,
3Department of Pathology, Université de Sherbrooke,
4Centre de Recherche du Centre Hospitalier de Universitaire de Sherbrooke, Université de Sherbrooke,
5Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas,
6UTSW Comprehensive Neurofibromatosis Clinic, University of Texas Southwestern Medical Center at Dallas,
7Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center at Dallas
1Cell Therapy Center, Beijing Municipal Geriatric Medical Research Center, Xuanwu Hospital Capital Medical University,
2National Clinical Research Center for Geriatric Diseases, and Key Laboratory of Neurodegenerative Diseases, Ministry of Education,
3The Department of Neurology, Xuanwu Hospital Capital Medical University
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