Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration
8.4K Views
•
06:14 min
•
May 9th, 2020
DOI :
May 9th, 2020
•Dmitry Frank*1, Israel Melamed*2, Benjamin F. Gruenbaum3, Julia Grinshpun1, Ruslan Kuts1, Rachel Shvartsur4, Abed N. Azab4, Mohamad H. Assadi5, Max Vinokur1, Matthew Boyko1
1Division of Anesthesia and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, 3Department of Anesthesiology, Yale University School of Medicine, 4Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, 5Department of microbiology and immunology, Faculty of Health Sciences, Ben-Gurion University of the Negev
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Chapters in this video
0:04
Introduction
0:45
Preparing Rats for the Experimental Procedure
1:11
Procedure of Induction Diffuse Axonal Brain Injury
1:54
Measurement of Rotational Kinematics, Biomechanical Parameters
2:32
Evaluation of Neurological Severity Score after 48 hours
3:08
Brain Collection for Histological Examination after 48 hours
4:02
Immunohistochemical Staining
4:16
Results
5:22
Conclusion
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