A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
9.6K Views
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09:49 min
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April 24th, 2020
DOI :
April 24th, 2020
•Maria Luisa Belli1, Emilio Mezzenga1, Valentina Di Iorio2, Monica Celli3, Paola Caroli3, Elisabeth Canali3, Federica Matteucci3, Elisa Tardelli3, Ilaria Grassi3, Maddalena Sansovini3, Silvia Nicolini3, Stefano Severi3, Marta Cremonesi4, Mahila Ferrari5, Giovanni Paganelli3, Anna Sarnelli1
1Medical Physics Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 2Oncology Pharmacy, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 3Nuclear Medicine Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 4Radiation Research Unit, Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy, 5Medical Physics Unit, Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy
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Chapters in this video
0:04
Introduction
1:24
Pre-Infusion Imaging: Transmission and Blank Image Acquisition
2:35
Post-Infusion Image Acquisition: Planar Image
3:21
Post-Infusion Image Acquisition: 3D SPECT/CT
3:51
Image Analysis
4:58
Blood Sample Measurements and Dosimetry Evaluation
5:50
Hybrid 2D+3D SCPET/CT Image Analysis
6:21
Adult Phantom Creation and Red Marrow Evaluation
7:50
Results: Representative Comparison of 2D, Hybrid 2D+3D, and 3D SPECT/CT Methods for Transient Intestine Uptake Overlap on Kidneys
8:35
Conclusion
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