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Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

6.4K Views

07:24 min

December 13th, 2018

DOI :

10.3791/58598-v

December 13th, 2018


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Multiple Myeloma

Chapters in this video

0:04

Title

0:56

Synthesis of Functionalized SWCNTs

1:53

Conjugation of Anti-MALAT1 Gapmer DNA Flanked by 2'-O Modified RNAs to Functionalized SWCNT

2:54

Tail Vein Injection of SWCNT-anti-MALAT1

4:14

Evaluation of the Disease Progression

5:01

Results: SWCNT-anti-MALAT1 Oligonucleotides Successfully Represses Multiple Myeloma Cell Growth

6:51

Conclusion

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