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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

17.1K Views

09:08 min

January 13th, 2017

DOI :

10.3791/54952-v

January 13th, 2017


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Natural Product

Chapters in this video

0:05

Title

0:54

Identification of a Natural Product with Antibiotic Property

3:54

Propose Biosynthetic Model of the New Isolated Compound

5:02

Identification of the Biosynthetic Gene Cluster

6:34

Verification of the Biosynthetic Gene Cluster

7:40

Results: HPLC Analysis of S. diastatochromogenes with Inactivated pokPI Gene

8:07

Conclusion

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