Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
23.3K Views
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07:13 min
•
March 26th, 2014
DOI :
March 26th, 2014
•Melanie R. Rutkowski*1, Michael J. Allegrezza*1, Nikolaos Svoronos1, Amelia J. Tesone1, Tom L. Stephen1, Alfredo Perales-Puchalt1, Jenny Nguyen1, Paul J. Zhang2, Steven N. Fiering3, Julia Tchou4,5,6, Jose R. Conejo-Garcia1
1Tumor Microenvironment and Metastasis Program, Wistar Institute, 2Department of Pathology and Lab Medicine, Perelman School of Medicine, University of Pennsylvania, 3Department of Microbiology and Immunology and Department of Genetics, Geisel School of Medicine at Dartmouth, 4Division of Endocrine and Oncologic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, 5Rena Rowan Breast Center, Abramson Cancer Center, University of Pennsylvania, 6Center for Advanced Medicine, University of Pennsylvania
Chapters in this video
0:05
Title
1:13
Intraductal Injection of Virus Particles
4:00
Results: Representative Tumor Formation and Metastasis
6:35
Conclusion
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