JoVE Logo

Zaloguj się

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

7.1K Views

08:59 min

December 11th, 2017

DOI :

10.3791/56583-v

December 11th, 2017


Przeglądaj więcej filmów

Acquired Resistance

Rozdziały w tym wideo

0:05

Title

1:39

Generation of Targeted Therapy Resistant Subclones

4:03

Restoring Target-therapy Inhibitor Sensitivity by Candidate R-gene Knock-down

6:31

Results: Drug Resistant Subclone Generation and Sensitivity Restoration

8:01

Conclusion

Powiązane Filmy

article

09:58

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models

13.6K Views

article

09:38

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

8.7K Views

article

07:42

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays

7.9K Views

article

10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

8.2K Views

article

12:28

Establishing Cell Lines Overexpressing DR3 to Assess the Apoptotic Response to Anti-mitotic Therapeutics

7.3K Views

article

09:38

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

7.9K Views

article

14:51

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype

3.1K Views

article

09:19

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

8.3K Views

article

08:46

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

10.5K Views

article

12:40

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

14.8K Views

JoVE Logo

Prywatność

Warunki Korzystania

Zasady

Badania

Edukacja

O JoVE

Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone